Diacylglycerol kinase zeta (DGKZ)

Displays a strong taste for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 action (PubMed:11257115).

Positively regulates insulin-induced translocation of SLC2A4 to the cell membrane in adipocytes (By similarity). Activates PIP5K1A action via generation of phosphatidic acid (PubMed:15157668).