DGKZ Antibodies

AND DGKZ ELISA kits, DGKZ Proteins

Many biological assays use antibodies to detect DGKZ, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DGKZ in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DGKZ antibodies...

We validate the specificity of these antibodies to DGKZ by testing them on tissues known to express DGKZ positively and negatively. Browse below to find the DGKZ antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for DGKZ? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the DGKZ Western Blot Guide

DGKZ Infographic by Boster Bio

All DGKZ Products

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Applications

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Anti-DGKZ/DGK-zeta Antibody Picoband®

Western blot analysis of DGKZ/DGK-zeta using anti-DGKZ/DGK-zeta antibody (A06678-2)

IHC analysis of DGKZ/DGK-zeta using anti-DGKZ/DGK-zeta antibody (A06678-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A06678-2
100 μg/vial

Anti-DGKZ Mouse Monoclonal Antibody [Clone ID: OTI1A6]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DGKZ (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 3 different cell lines by using anti-DGKZ monoclonal antibody (1:500)

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-DGKZ mouse monoclonal antibody

Human, Mouse, Rat

IHC, WB

$523
Cat # M06678
100 µl

DGKZ (NM_003646) Human Over-expression Lysate

Human

$628
Cat # LS008525
20 µg, 100 µg

Anti-Diacylglycerol kinase zeta DGKZ Antibody

Western blot analysis of extracts of various cell lines, using DGKZ antibody

Human, Mouse

$405
Cat # A06678-1
100ul

Anti-DGKZ/Dgk Zeta Antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using DGKZ Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC

$335
Cat # A06678
100ul

DGKZ Overview

Facts about Diacylglycerol kinase zeta.

DGKZ 3D structure. Source: alphafold

Diacylglycerol kinase zeta (DGKZ)

Displays a strong taste for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 action (PubMed:11257115).

Positively regulates insulin-induced translocation of SLC2A4 to the cell membrane in adipocytes (By similarity). Activates PIP5K1A action via generation of phosphatidic acid (PubMed:15157668).

Gene Information

Human
Gene Name:	DGKZ
Uniprot:	Q13574
Entrez:	8525

Family

Belongs to:

eukaryotic diacylglycerol kinase family

Alternative Names

DAGK5; DAGK6DAG kinase zeta; DGKZ; DGKzeta; DGK-zeta; diacylglycerol kinase zeta; diacylglycerol kinase, zeta 104kDa; diacylglycerol kinase, zeta; Diglyceride kinase zeta; EC 2.7.1.107; hDGKzeta

Molecular Weight

Mass (kDA):
124.128 kDA

Genomic Context


Human

Location:	11p11.2
Sequence:	11; NC_000011.10 (46332905..46380554)

Tissue Specificity

Highest levels in brain, and substantial levels in skeletal muscle, heart, and pancreas. Isoform 1 is predominantly expressed in muscle.

Subcellular Localizations

Cytoplasm. Nucleus. Cell membrane. Cell projection, lamellipodium.

Diseases

Malignant Neoplasms
Neoplasms
Neoplasm Metastasis
Impacted Tooth
Chromosome 11, Deletion 11p
Pituitary Diseases
Schizophrenia
Malignant Paraganglionic Neoplasm

Pituitary Neoplasms
Bipolar Disorder
Prolactinoma

Interacting Proteins

RB1
RBL1
RBL2

Pathways

Methylation
Histone Acetylation
Dna Methylation
Regulation Of Gene Expression
Cognition

PTMs

Acetylation

Methylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DGKZ

References

PMID: 8626588 by Bunting M., et al. Molecular cloning and characterization of a novel human diacylglycerol kinase zeta.

PMID: 9159104 by Ding L., et al. Alternative splicing of the human diacylglycerol kinase zeta gene in muscle.