- Table of Content
Required for cytokinesis, and transcriptional activation of the serum response factor (By similarity). DFR proteins bunch Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).
|formin homology family|
|Sequence:||5; NC_000005.10 (141515016..141619055, complement)|
Expressed in brain, heart, placenta, lung, kidney, pancreas, liver, skeletal muscle and cochlea. Expressed in platelets (PubMed:26912466).
Cell membrane. Cell projection, ruffle membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Nucleus. Membrane ruffles, especially at the tip of ruffles, of motile cells.