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- Table of Contents
Delta-like protein 4 Antibodies
AND Dll4 ELISA kits, Delta-like protein 4 Proteins
Many biological assays use antibodies to detect Delta-like protein 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Delta-like protein 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Delta-like protein 4 antibodies...
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Dll4 Infographic by Boster Bio
All Dll4 Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$499
Cat # EK1277
96 wells/kit, with removable strips.
Cat # EK1277
96 wells/kit, with removable strips.
Anti-DLL4 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00875-4
100 µg/vial
Cat # A00875-4
100 µg/vial
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00875
100 μg
Cat # M00875
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00875-1
100 μg
Cat # M00875-1
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00875-2
100 μg
Cat # M00875-2
100 μg
Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00875-3
100 μg
Cat # M00875-3
100 μg
Dll4 Overview
Facts about Delta-like protein 4.
Delta-like protein 4 (Dll4)
Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4.
Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (By similarity). Essential for retinal progenitor proliferation.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Dll4 |
| Uniprot: | Q9JI71 |
| Entrez: | 54485 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Delta 4 precursor; delta 4; delta ligand 4; delta4; delta-like 4 (Drosophila); delta-like 4 homolog (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4
Molecular Weight
Mass (kDA):
74.991 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 2|2 E5 |
| Sequence: | 2; |
Tissue Specificity
Expressed in vascular endothelium. Expressed in retina at least during embryogenesis.
Diseases
- Tumor Angiogenesis
- Neoplasms
- Pathologic Neovascularization
- Malignant Neoplasms
- Hypoxia
- Carcinoma
- Leukemia
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Malignant Paraganglionic Neoplasm
- Cell Invasion
Pathways
- Angiogenesis
- Cell Proliferation
- Notch Signaling Pathway
- Cell Differentiation
- Sprouting Angiogenesis
- Pathogenesis
- Cell Development
- Cell Cycle
- Cell Growth
- Localization
- Endothelial Cell Proliferation
- Cell Migration
- Vasculogenesis
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dll4
bosterbio.com/bosterbio-gene-info-cards/Dll4
References
PMID: 10837024 by Shutter J.R., et al. Dll4, a novel Notch ligand expressed in arterial endothelium.
PMID: 11134954 by Yoneya T., et al. Molecular cloning of Delta-4, a new mouse and human Notch ligand.