DMC1 Antibodies

AND DMC1 ELISA kits, DMC1 Proteins

Many biological assays use antibodies to detect DMC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DMC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DMC1 antibodies...

We validate the specificity of these antibodies to DMC1 by testing them on tissues known to express DMC1 positively and negatively. Browse below to find the DMC1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DMC1 Infographic by Boster Bio

All DMC1 Products

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Specificity

Applications

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Anti-DMC1 Antibody

3 Q&As

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using DMC1 Antibody

Human, Mouse

ELISA, IF, IHC, ICC

$335
Cat # A02978
100ul

Anti-DMC1 Antibody

Western blot analysis of extracts of various cell lines, using DMC1 antibody at 1:1000 dilution

Western blot analysis of extracts of Rat testis, using DMC1 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A02978-1
100ul

Anti-DMC1 Antibody Picoband®

Western blot analysis of DMC1 using anti-DMC1 antibody (A02978-3)

IHC analysis of DMC1 using anti-DMC1 antibody (A02978-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A02978-3
100 μg/vial

DMC1 (NM_007068) Human Over-expression Lysate

Human

$628
Cat # LS011144
20 µg, 100 µg

DMC1 Overview

Facts about Meiotic recombination protein DMC1/LIM15 homolog.

DMC1 3D structure. Source: alphafold

Meiotic recombination protein DMC1/LIM15 homolog (DMC1)

May participate in meiotic recombination, specifically in homologous strand assimilation, which is needed for the resolution of meiotic double-strand breaks. .

Gene Information

Human
Gene Name:	DMC1
Uniprot:	Q14565
Entrez:	11144

Family

Belongs to:

RecA family

Alternative Names

disrupted meiotic cDNA1, yeast, homolog of; DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologousrecombination (yeast); DMC1 homologue; HsLim15; LIM15yeast homolog) meiosis-specific homologousrecombination; meiotic recombination protein DMC1/LIM15 homolog; MGC150472; MGC150473

Molecular Weight

Mass (kDA):
37.681 kDA

Genomic Context


Human

Location:	22q13.1
Sequence:	22; NC_000022.11 (38509154..38570286, complement)

Subcellular Localizations

Nucleus. Chromosome.

Diseases

Cell Invasion
Malignant Neoplasms
Infertility
Neoplasms
Sterility
Polyploidy
Malignant Neoplasm Of Breast
Aneuploidy
Male Infertility
Female Infertility
Cytogenetic Abnormality
Premature Menopause
Ovarian Failure, Premature

Azoospermia
Mammary Neoplasms
Anemia
Genomic Instability
Malignant Neoplasm Of Esophagus
Keratoderma, Palmoplantar, Diffuse
Triploidy

Interacting Proteins

BRCA2
GORASP2
KCTD17
NIF3L1
PSMA3

SDCBP
TRIM23

Pathways

Meiosis
Prophase
Dna Repair
Pachytene
Chromosome Segregation
Cell Cycle
Strand Invasion
Localization
Recombinational Repair
Meiosis I
Mitosis
Spermatogenesis
Metaphase

Zygotene
Double-strand Break Repair
Sporulation
Dna Recombination
Dna Replication
Meiotic Recombination Checkpoint
Meiotic Prophase I

PTMs

Phosphorylation
Sumoylation
Cleavage

Methylation
Demethylation
Iodination

Research Areas

Apoptosis
Cancer
Cell Cycle and Replication
Chromatin Research
DNA Repair

Homologous Recombination
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DMC1

References

PMID: 8590282 by Sato S., et al. Expression profiles of a human gene identified as a structural homologue of meiosis-specific recA-like genes.

PMID: 8602360 by Habu T., et al. The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon- skipped transcript in meiosis.