DUSP2 Antibodies

AND DUSP2 ELISA kits, DUSP2 Proteins

Many biological assays use antibodies to detect DUSP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DUSP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DUSP2 antibodies...

We validate the specificity of these antibodies to DUSP2 by testing them on tissues known to express DUSP2 positively and negatively. Browse below to find the DUSP2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DUSP2 Infographic by Boster Bio

All DUSP2 Products

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Product

Figures

Specificity

Applications

Price

DUSP2 (NM_004418) Human Over-expression Lysate

Human

$628
Cat # LS001844
20 µg, 100 µg

Anti-PAC1 Reference Antibody (zelminemab)

The purity of Anti-PAC1 Reference Antibody (zelminemab)is more than 99

Cynomolgus monkey, Human, Mouse

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M06043
100 μg

Anti-DUSP2 Antibody Picoband®

Western blot analysis of DUSP2 using anti-DUSP2 antibody (A06043-1)

IHC analysis of DUSP2 using anti-DUSP2 antibody (A06043-1)

IF analysis of DUSP2 using anti-DUSP2 antibody (A06043-1) and anti-Alpha Tubulin antibody (M03989-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06043-1
100 μg/vial

DUSP2 Overview

Facts about Dual specificity protein phosphatase 2.

DUSP2 3D structure. Source: alphafold

Dual specificity protein phosphatase 2 (DUSP2)

Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. .

Gene Information

Human
Gene Name:	DUSP2
Uniprot:	Q05923
Entrez:	1844

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

dual specificity protein phosphatase 2; PAC-1; dual specificity phosphatase 2; PAC1

Molecular Weight

Mass (kDA):
34.4 kDA

Genomic Context


Human

Location:	2q11.2
Sequence:	2; NC_000002.12 (96143166..96145468, complement)

Tissue Specificity

Expressed in hematopoietic tissues.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Inflammation
Malignant Neoplasms
Hemorrhage
Tissue Adhesions
Cardiovascular Diseases
Thrombosis
Coronary Artery Disease
Hypoxia
Pituitary Diseases
Infarction
Inflammatory Response
Myocardial Infarction

Bleeding Tendency
Melanoma
Tumor Angiogenesis
Lymphoma
Rheumatoid Arthritis
Postoperative Hemorrhage
Angina Pectoris

Pathways

Platelet Activation
Platelet Aggregation
Secretion
Cell Proliferation
Coagulation
Immune Response
Inflammatory Response
Hemostasis
Localization
Cell Adhesion
Proteolysis
Hypersensitivity
Cell Cycle

Angiogenesis
Pathogenesis
Cell Activation
Gene Silencing
Osteoblast Differentiation
B Cell Activation
Cell Cycle Arrest

PTMs

Phosphorylation
Dephosphorylation
Cleavage
Demethylation

Nitration
Carboxylation
Biotinylation
Methylation

Palmitoylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DUSP2

References

PMID: 7681221 by Rohan P., et al. PAC-1: a mitogen-induced nuclear protein tyrosine phosphatase.

PMID: 7590752 by Yi H., et al. Genomic organization and chromosomal localization of the DUSP2 gene, encoding a MAP kinase phosphatase, to human 2p11.2-q11.