This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Dgat2 Antibodies
AND Dgat2 ELISA kits, Dgat2 Proteins
Many biological assays use antibodies to detect Dgat2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dgat2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dgat2 antibodies...
Designing a Western blot for Dgat2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DGAT2 Western Blot GuideDgat2 Infographic by Boster Bio
All Dgat2 Products
Product
Figures
Specificity
Applications
Price
Dgat2 Overview
Facts about Diacylglycerol O-acyltransferase 2.
Diacylglycerol O-acyltransferase 2 (Dgat2)
Essential acyltransferase which catalyzes the terminal and just committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides.
Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids to triglycerides.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Dgat2 |
| Uniprot: | Q9DCV3 |
| Entrez: | 67800 |
Family
| Belongs to: |
|---|
| diacylglycerol acyltransferase family |
Alternative Names
DGAT2; diacylglycerol O-acyltransferase 2; diacylglycerol O-acyltransferase homolog 2 (mouse); diacylglycerol O-acyltransferase homolog 2; diacylglycerol O-acyltransferase-like protein 2; Diglyceride acyltransferase 2; DKFZp686A15125; EC 2.3.1; EC 2.3.1.20; GS1999FULL
Molecular Weight
Mass (kDA):
43.77 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 7|7 E1 |
| Sequence: | 7; |
Tissue Specificity
Predominantly expressed in liver. Also expressed in testis.
Diseases
- Obesity
- Steatosis
- Fatty Liver
- Insulin Resistance
- Steatohepatitis
- Diabetes Mellitus
- Insulin Sensitivity
- Inflammation
- Liver Diseases
- Dyslipidemias
- Hyperlipidemia
- Nonalcoholic Fatty Liver Disease
- Atherosclerosis
Pathways
- Secretion
- Localization
- Fatty Acid Oxidation
- Transport
- Pathogenesis
- Gene Silencing
- Tissue Development
- Fatty Acid Transport
- Lipid Homeostasis
- Parturition
- Adipose Tissue Development
- Energy Homeostasis
- Macrophage Activation
PTMs
- Oxidation
- Acylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dgat2
bosterbio.com/bosterbio-gene-info-cards/Dgat2
References
PMID: 11481335 by Cases S., et al. Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.
PMID: 12413942 by Meegalla R.L., et al. Concerted elevation of acyl-coenzyme A:diacylglycerol acyltransferase (DGAT) activity through independent stimulation of mRNA expression of DGAT1 and DGAT2 by carbohydrate and insulin.