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- Table of Contents
Facts about Endothelin-converting enzyme 1.
Human | |
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Gene Name: | ECE1 |
Uniprot: | P42892 |
Entrez: | 1889 |
Belongs to: |
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peptidase M13 family |
EC 3.4.24; EC 3.4.24.71; ECE; ECE1; ECE-1; endothelin converting enzyme 1; endothelin-converting enzyme 1
Mass (kDA):
87.164 kDA
Human | |
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Location: | 1p36.12 |
Sequence: | 1; NC_000001.11 (21217250..21345504, complement) |
All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C in liver, testis and small intestine; isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney.
Cell membrane; Single-pass type II membrane protein.
PMID: 7695628 by Yorimitsu K., et al. Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2.
PMID: 7864876 by Shimada K., et al. Cloning and functional expression of human endothelin-converting enzyme cDNA.
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