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- Table of Contents
EDIL3 Antibodies
AND EDIL3 ELISA kits, EDIL3 Proteins
Many biological assays use antibodies to detect EDIL3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EDIL3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EDIL3 antibodies...
Designing an IHC experiment for EDIL3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the EDIL3 IHC GuideEDIL3 Infographic by Boster Bio
All EDIL3 Products
Product
Figures
Specificity
Applications
Price
Human EDIL3 ELISA Kit PicoKine®
1 Citations
Human
ELISA
$750
Cat # EK1500
96 wells/kit, with removable strips.
Cat # EK1500
96 wells/kit, with removable strips.
EDIL3 Overview
Facts about EGF-like repeat and discoidin I-like domain-containing protein 3.
EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3)
Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures.
May be involved in regulation of vascular morphogenesis of remodeling in embryonic development. .
Gene Information
| Human | |
|---|---|
| Gene Name: | EDIL3 |
| Uniprot: | O43854 |
| Entrez: | 10085 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DEL1; DEL1developmental endothelial locus-1; Developmentally-regulated endothelial cell locus 1 protein; EDIL3; EGF-like repeat and discoidin I-like domain-containing protein 3; EGF-like repeats and discoidin I-like domains 3; Integrin-binding protein DEL1; MGC26287
Molecular Weight
Mass (kDA):
53.765 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q14.3 |
| Sequence: | 5; NC_000005.10 (83940554..84384880, complement) |
Subcellular Localizations
Secreted.
Diseases
- Tumor Angiogenesis
- Tissue Adhesions
- Neoplasms
- Carcinoma
- Ischemia
- Peripheral Arterial Diseases
- Arteriopathic Disease
- Malignant Neoplasms
- Pathologic Neovascularization
- Osteosarcoma
- Alveolar Bone Loss
- Peripheral Vascular Diseases
Pathways
- Angiogenesis
- Cell Adhesion
- Cell Proliferation
- Endocytosis
- Endothelial Cell Proliferation
- Cell Growth
- Lactation
- Aging
- Immune Response
- Dna Methylation
- Vasculogenesis
- Methylation
- Cartilage Development
PTMs
- Disulfide bond
Research Areas
- Angiogenesis
- Cell Biology
- Cellular Markers
- Endothelial Cell Markers
- Extracellular Matrix
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDIL3
bosterbio.com/bosterbio-gene-info-cards/EDIL3
References
PMID: 9420328 by Hidai C., et al. Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor.
PMID: 22601780 by Schurpf T., et al. The RGD finger of Del-1 is a unique structural feature critical for integrin binding.