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- Table of Contents
EDNRB Antibodies
AND EDNRB ELISA kits, EDNRB Proteins
Many biological assays use antibodies to detect EDNRB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EDNRB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EDNRB antibodies...
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EDNRB Infographic by Boster Bio
All EDNRB Products
Product
Figures
Specificity
Applications
Price
Anti-Endothelin B Receptor/EDNRB Antibody Picoband®
2 Citations 1 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9554
100 μg/vial
Cat # PB9554
100 μg/vial
Anti-EDNRB Antibody Picoband® (monoclonal, 15C3)
1 Citations 6 Q&As
Human
WB
$370
Cat # M01041-1
100 μg/vial
Cat # M01041-1
100 μg/vial
Human
$628
Cat # LS001910
20 µg, 100 µg
Cat # LS001910
20 µg, 100 µg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01041-2
100 μg
Cat # M01041-2
100 μg
EDNRB Overview
Facts about Endothelin receptor type B.
Endothelin receptor type B (EDNRB)
Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | EDNRB |
| Uniprot: | P24530 |
| Entrez: | 1910 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
ABCDS; EDNRB; endothelin B receptor; Endothelin receptor non-selective type; endothelin receptor type B; ETB; ET-B; ETBR; ET-BR; ETRB; HSCR; HSCR2; WS4A
Molecular Weight
Mass (kDA):
49.644 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q22.3 |
| Sequence: | 13; NC_000013.11 (77895481..77975527, complement) |
Tissue Specificity
Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. internalized after activation by endothelins.
Diseases
- Hirschsprung Disease
- Crest Syndrome
- Nervousness
- Neoplasms
- Malignant Neoplasms
- Waardenburg Syndrome
- Megacolon
- Carcinoma
- Metrorrhagia
- Complete Hearing Loss
- Sensorineural Hearing Loss (disorder)
- Waardenburg Syndrome, Type 4a
- Congenital Abnormality
Interacting Proteins
- EDN1
Pathways
- Methylation
- Pathogenesis
- Pigmentation
- Dna Methylation
- Cell Proliferation
- Innervation
- Localization
- Cell Migration
- Melanocyte Differentiation
- Cell Development
- Cell Adhesion
- System Development
- Demethylation
PTMs
- Methylation
- Demethylation
Research Areas
- GPCR
- Neuroscience
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDNRB
bosterbio.com/bosterbio-gene-info-cards/EDNRB
References
PMID: 1710450 by Nakamuta M., et al. Cloning and sequence analysis of a cDNA encoding human non-selective type of endothelin receptor.
PMID: 1648908 by Ogawa Y., et al. Molecular cloning of a non-isopeptide-selective human endothelin receptor.
3 Publications of Boster EDNRB Antibodies & ELISA Kits
- PubMed ID: 10.1159/000157628, Normalizing NADPH Oxidase Contributes to Attenuating Diabetic Nephropathy by the...
- PubMed ID: 10.1080/03079457.2013.821568, Expression of endothelin-1 and its receptors in the lungs of broiler chickens ex...
- PubMed ID: 20167215, Peng Hj, Dai Dz, Ji H, Dai Y. Eur J Pharmacol. 2010 May 25;634(1-3):101-6. Doi: ...
*More publications can be found for each product on its corresponding product page