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- Table of Contents
EFEMP1 Antibodies
AND EFEMP1 ELISA kits, EFEMP1 Proteins
Many biological assays use antibodies to detect EFEMP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EFEMP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EFEMP1 antibodies...
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EFEMP1 Infographic by Boster Bio
All EFEMP1 Products
Product
Figures
Specificity
Applications
Price
Human Fibulin-3/EFEMP1 ELISA Kit PicoKine®
2 Citations 10 Q&As
Human
ELISA
$750
Cat # EK1468
96 wells/kit, with removable strips.
Cat # EK1468
96 wells/kit, with removable strips.
Mouse
ELISA
$750
Cat # EK1590
96 wells/kit, with removable strips.
Cat # EK1590
96 wells/kit, with removable strips.
Human, Mouse, Rat
Flow Cytometry, WB
$523
Cat # M02302
100 µl
Cat # M02302
100 µl
EFEMP1 Overview
Facts about EGF-containing fibulin-like extracellular matrix protein 1.
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1)
Binds EGFR, the EGF receptor, causing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration.
May be a negative regulator of chondrocyte differentiation. From the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
Gene Information
| Human | |
|---|---|
| Gene Name: | EFEMP1 |
| Uniprot: | Q12805 |
| Entrez: | 2202 |
Family
| Belongs to: |
|---|
| fibulin family |
Alternative Names
DHRD; EFEMP1; EGF containing fibulin-like extracellular matrix protein 1; EGF-containing fibulin-like extracellular matrix protein 1; Extracellular protein S1-5; FBLN3; FBLN3DRAD; FBNLFLJ35535; FIBL-3; Fibrillin-like protein; fibrillin-like; Fibulin 3; fibulin-3; MGC111353; MLVT; MTLV; S1-5
Molecular Weight
Mass (kDA):
54.641 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p16.1 |
| Sequence: | 2; NC_000002.12 (55865967..55924163, complement) |
Tissue Specificity
In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina.
Subcellular Localizations
Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Localizes to the lamina propria underneath the olfactory epithelium.
Diseases
- Age Related Macular Degeneration
- Neoplasms
- Dystrophy
- Malignant Neoplasms
- Retinal Dystrophies
- Retinal Drusen
- Tumor Angiogenesis
- Neoplasm Metastasis
- Carcinoma
- Pathologic Neovascularization
- Blind Vision
- Cell Invasion
Interacting Proteins
- ARAF
- ATN1
- BAG6
- CRYBA4
- MEOX2
- SGTA
- TRAF2
- UBQLN2
Pathways
- Methylation
- Angiogenesis
- Pathogenesis
- Cell Proliferation
- Dna Methylation
- Cell Growth
- Senescence
- Regeneration
- Cell Death
- Aging
- Complement Activation
- Cell Communication
- Demethylation
PTMs
- Methylation
Research Areas
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EFEMP1
bosterbio.com/bosterbio-gene-info-cards/EFEMP1
References
PMID: 7799918 by Lecka-Czernik B., et al. An overexpressed gene transcript in senescent and quiescent human fibroblasts encoding a novel protein in the epidermal growth factor- like repeat family stimulates DNA synthesis.
PMID: 8812496 by Ikegawa S., et al. Structure and chromosomal assignment of the human S1-5 gene (FBNL) that is highly homologous to fibrillin.
1 Publications of Boster EFEMP1 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.jtho.2021.05.018, SERUM PROTEOMICS AND PLASMA FIBULIN-3 IN DIFFERENTIATION OF MESOTHELIOMA FROM AS...
*More publications can be found for each product on its corresponding product page