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- Table of Contents
EGR1 Antibodies
AND EGR1 ELISA kits, EGR1 Proteins
Many biological assays use antibodies to detect EGR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EGR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EGR1 antibodies...
Designing a Western blot for EGR1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the EGR1 Western Blot GuideEGR1 Infographic by Boster Bio
All EGR1 Products
Product
Figures
Specificity
Applications
Price
Anti-EGR1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00687-3
100 μg/vial
Cat # A00687-3
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1685
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1685
1 kit, containing one 96-well plate and all necessary reagents
EGR1 Overview
Facts about Early growth response protein 1.
Early growth response protein 1 (EGR1)
Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double- stranded target DNA, irrespective of the cytosine methylation status (PubMed:25258363, PubMed:25999311).
Regulates the transcription of numerous target genes, and thus plays a significant role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.
Gene Information
| Human | |
|---|---|
| Gene Name: | EGR1 |
| Uniprot: | P18146 |
| Entrez: | 1958 |
Family
| Belongs to: |
|---|
| EGR C2H2-type zinc-finger protein family |
Alternative Names
AT225Transcription factor ETR103; early growth response 1; early growth response protein 1; EGR1; EGR-1; G0S30; KROX24; KROX-24; Nerve growth factor-induced protein A; NGFIA; NGFI-ATranscription factor Zif268; TIS8; ZIF-268; Zinc finger protein Krox-24; ZNF225; ZNF225Zinc finger protein 225
Molecular Weight
Mass (kDA):
57.507 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q31.2 |
| Sequence: | 5; NC_000005.10 (138465479..138469303) |
Tissue Specificity
Detected in neutrophils (at protein level).
Subcellular Localizations
Nucleus. Cytoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Carcinoma
- Leukemia
- Nervousness
- Tissue Adhesions
- Tumor Angiogenesis
- Cell Transformation, Neoplastic
- Hypoxia
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Nephroblastoma
Interacting Proteins
- CDKN2A
- CTNNB1
Pathways
- Cell Proliferation
- Cell Growth
- Cell Cycle
- Pathogenesis
- Cell Death
- Localization
- Secretion
- Angiogenesis
- Methylation
- Cell Differentiation
- Cell Activation
- Translation
- Regeneration
PTMs
- Phosphorylation
- Methylation
- Acetylation
- Cleavage
- Dephosphorylation
- Demethylation
- Phosphorothioation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EGR1
bosterbio.com/bosterbio-gene-info-cards/EGR1
References
PMID: 2377485 by Suggs S.V., et al. cDNA sequence of the human cellular early growth response gene Egr- 1.
PMID: 1569051 by Shimizu N., et al. A gene coding for a zinc finger protein is induced during 12-O- tetradecanoylphorbol-13-acetate-stimulated HL-60 cell differentiation.
4 Publications of Boster EGR1 Antibodies & ELISA Kits
- PubMed ID: PMID:28682429, Study on the expression and mechanism of inflammatory factors in the brain of ra...
- PubMed ID: 10.3892/or.2011.1163, GROβ and its downstream effector EGR1 regulate cisplatin-induced apoptosis in W...
- PubMed ID: 10.3390/ijms20071548, Identification, Characterization, and Regulatory Mechanisms of a Novel EGR1 Spli...
- PubMed ID: 24925646, Lin K, Fang S, Cai B, Huang X, Zhang X, Lu Y, Zhang W, Wei E. Eur J Cell Biol. 2...
*More publications can be found for each product on its corresponding product page