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- Table of Contents
EGR2 Antibodies
AND EGR2 ELISA kits, EGR2 Proteins
Many biological assays use antibodies to detect EGR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EGR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EGR2 antibodies...
Designing a Western blot for EGR2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the EGR2 Western Blot GuideEGR2 Infographic by Boster Bio
All EGR2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00921-1
100 μg/vial
Cat # A00921-1
100 μg/vial
EGR2 Overview
Facts about E3 SUMO-protein ligase EGR2.
E3 SUMO-protein ligase EGR2 (EGR2)
Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4.
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Gene Information
| Human | |
|---|---|
| Gene Name: | EGR2 |
| Uniprot: | P11161 |
| Entrez: | 1959 |
Family
| Belongs to: |
|---|
| EGR C2H2-type zinc-finger protein family |
Alternative Names
AT591; CMT1D; CMT4E; early growth response 2 (Krox-20 homolog, Drosophila); early growth response 2; early growth response protein 2; EGR-2; FLJ14547; Krox-20 homolog, Drosophila; KROX-20, Drosophila, homolog (early growth response-2); KROX20DKFZp686J1957; Zinc finger protein Krox-20
Molecular Weight
Mass (kDA):
50.302 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q21.3 |
| Sequence: | 10; NC_000010.11 (62811996..62819167, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Charcot-marie-tooth Disease
- Nervousness
- Peripheral Neuropathy
- Neoplasms
- Crest Syndrome
- Hereditary Motor And Sensory Neuropathies
- Malignant Neoplasms
- Congenital Hypomyelinating Neuropathy
- Demyelinating Diseases
- Dejerine-sottas Disease (disorder)
- Inherited Neuropathy
- Tissue Adhesions
Pathways
- Myelination
- Segmentation
- Cell Cycle
- Cell Proliferation
- Cell Development
- Pathogenesis
- Hindbrain Development
- Schwann Cell Development
- Cell Differentiation
- Cell Death
- Regeneration
- Cell Activation
- Localization
PTMs
- Phosphorylation
- Methylation
- Acetylation
- Cleavage
Research Areas
- Chromatin Research
- Neurodegeneration
- Neuroscience
- Transcription Factors and Regulators
- Zinc Finger
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EGR2
bosterbio.com/bosterbio-gene-info-cards/EGR2
References
PMID: 3140236 by Joseph L.J., et al. Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with 'zinc-binding finger' structure.
PMID: 9537424 by Warner L.E., et al. Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies.