EI24 Antibodies

AND EI24 ELISA kits, EI24 Proteins

Many biological assays use antibodies to detect EI24, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EI24 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EI24 antibodies...

We validate the specificity of these antibodies to EI24 by testing them on tissues known to express EI24 positively and negatively. Browse below to find the EI24 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for EI24? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the EI24 IHC Guide

EI24 Infographic by Boster Bio

All EI24 Products

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Anti-EI24 Antibody

Western blot analysis of EI24 in rat liver tissue lysate with EI24 antibody at (A) 1 and (B) 2 μg/mL

Immunohistochemistry of EI24 in rat liver tissue with EI24 antibody at 5 μg/mL

Human, Mouse, Rat

ELISA, IHC-P, WB

$481
Cat # A06183
0.1 mg

EI24 (NM_004879) Human Over-expression Lysate

Human

$628
Cat # LS009538
20 µg, 100 µg

EI24 Overview

Facts about Etoposide-induced protein 2.4 homolog.

EI24 3D structure. Source: alphafold

Etoposide-induced protein 2.4 homolog (EI24)

Acts as a negative growth regulator through p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes through autophagy (By similarity).

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Gene Information

Human
Gene Name:	EI24
Uniprot:	O14681
Entrez:	9538

Family

Belongs to:

EI24 family

Alternative Names

EPG4; etoposide induced 2.4 mRNA; p53-induced gene 8 protein; PIG8etoposide-induced protein 2.4 homolog; TP53I8; tumor protein p53 inducible protein 8

Molecular Weight

Mass (kDA):
38.965 kDA

Genomic Context


Human

Location:	11q24.2
Sequence:	11; NC_000011.10 (125569216..125584684)

Subcellular Localizations

Nucleus membrane; Multi-pass membrane protein. Cytoplasm. Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Carcinogenesis
Growth Retardation
Carcinoma
Glaucoma
Neoplasm Metastasis
Intraepithelial Neoplasia
Metastatic Malignant Neoplasm To The Lymph Node
Melanoma
Myxoid Dermatofibrosarcoma Protuberans

Neoplasm Invasiveness
Malignant Tumor Of Cervix
Sarcoma
Nerve Transections, Optic
Neoplasm/cancer Invasiveness
Cervical Intraepithelial Neoplasia
Anaplasia

Pathways

Cell Cycle
Autophagy
Cell Proliferation
Localization
Cell Cycle Arrest
Methylation
Cell Death
Cell Growth
Response To Radiation
Cellular Response To Radiation

Response To Stress
Induction Of Apoptosis
Osteoblast Differentiation
Dedifferentiation

PTMs

Methylation

Phosphorylation

Cleavage

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EI24

References

PMID: 9305847 by Polyak K., et al. A model for p53-induced apoptosis.

PMID: 11753653 by Gentile M., et al. Candidate tumour suppressor genes at 11q23-q24 in breast cancer: evidence of alterations in PIG8, a gene involved in p53-induced apoptosis.