EIF2B3 Antibodies

AND EIF2B3 ELISA kits, EIF2B3 Proteins

Many biological assays use antibodies to detect EIF2B3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF2B3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF2B3 antibodies...

We validate the specificity of these antibodies to EIF2B3 by testing them on tissues known to express EIF2B3 positively and negatively. Browse below to find the EIF2B3 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF2B3 Infographic by Boster Bio

All EIF2B3 Products

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Anti-eIF2B gamma EIF2B3 Antibody

4 Q&As

Western Blot analysis of various cells using eIF2Bγ Polyclonal Antibody diluted at 1:1000

Western Blot analysis of K562 cells using eIF2Bγ Polyclonal Antibody diluted at 1:1000

Human, Mouse

ELISA, WB

$399
Cat # A08134
100μl

Anti-EIF2B3 Antibody

Western blot analysis of extracts of various cell lines, using EIF2B3 antibody at 1:1000 dilution

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A08134-1
100ul

Anti-EI2BG Antibody

Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0

All lanes : Anti-EI2BG Antibody at 1:2000 dilutionLane 1: HL-60 whole cell lysateLane 2: MCF-7 whole cell lysateLane 3: U-2OS whole cell lysateLane 4: K562 whole cell lysateLysates/proteins at 20 µg per lane

Overlay histogram showing U-2 OS cells stained with M08134 (green line)

Human

Flow Cytometry, IF, WB

$299
Cat # M08134
50 µl

Anti-EIF2B3 Mouse Monoclonal Antibody [Clone ID: OTI1A4]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EIF2B3 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-EIF2B3 monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-EIF2B3 mouse monoclonal antibody

Dog, Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M08134-1
100 µl

EIF2B3 (NM_020365) Human Over-expression Lysate

EIF2B3 Human Over-expression Lysates NM_001166588

Human

$960
Cat # LS008891
20 µg, 100 µg

Anti-EIF2B3 Antibody

Human, Mouse

ELISA, IF, IHC, ICC, WB

$370
Cat # A08134-2
100 μl/vial

EIF2B3 Overview

Facts about Translation initiation factor eIF-2B subunit gamma.

EIF2B3 3D structure. Source: alphafold

Translation initiation factor eIF-2B subunit gamma (EIF2B3)

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. .

Gene Information

Human
Gene Name:	EIF2B3
Uniprot:	Q9NR50
Entrez:	8891

Family

Belongs to:

eIF-2B gamma/epsilon subunits family

Alternative Names

eIF-2B GDP-GTP exchange factor subunit gamma; EIF-2B; EIF2Bgamma; eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD); eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; translation initiation factor eIF-2B subunit gamma

Molecular Weight

Mass (kDA):
50.24 kDA

Genomic Context


Human

Location:	1p34.1
Sequence:	1; NC_000001.11 (44850522..44986722, complement)

Diseases

Leukoencephalopathies
Premature Menopause
Parkinson Disease
Ovarian Failure, Premature
Brain Diseases
Optic Atrophy
Amenorrhea
Ataxia
Confusion
Leukoencephalopathy With Vanishing White Matter
Primary Physiologic Amenorrhea

Immunologic Deficiency Syndromes
Neoplasms
Nervousness
Headache
Muscle Spasticity

Pathways

Translation
Cell Death

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF2B3

References

PMID: 10900014 by Krueger M., et al. Identification of eIF2B gamma and eIF2 gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach.

PMID: 11835386 by van der Knaap M.S., et al. Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter.