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- Table of Contents
EIF4A1 Antibodies
AND EIF4A1 ELISA kits, EIF4A1 Proteins
Many biological assays use antibodies to detect EIF4A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF4A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF4A1 antibodies...
Designing a Western blot for EIF4A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the EIF4A1 Western Blot GuideEIF4A1 Infographic by Boster Bio
All EIF4A1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03922-2
100 μg/vial
Cat # A03922-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03922-2
100 μg/vial
Cat # M03922-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03922-3
100 μg/vial
Cat # A03922-3
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03922-1
100 μg/vial
Cat # M03922-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M03922-3
100 μl/vial
Cat # M03922-3
100 μl/vial
EIF4A1 Overview
Facts about Eukaryotic initiation factor 4A-I.
Eukaryotic initiation factor 4A-I (EIF4A1)
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the present version of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs that's necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
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Gene Information
| Human | |
|---|---|
| Gene Name: | EIF4A1 |
| Uniprot: | P60842 |
| Entrez: | 1973 |
Family
| Belongs to: |
|---|
| DEAD box helicase family |
Alternative Names
ATP-dependent RNA helicase eIF4A-1; DDX2Aeukaryotic initiation factor 4A-I; EC 3.6.1; EC 3.6.4.13; EIF4A; EIF-4A; eIF-4A-I; eIF4A-I; eukaryotic initiation factor 4AI; eukaryotic translation initiation factor 4A; eukaryotic translation initiation factor 4A, isoform 1; eukaryotic translation initiation factor 4A1
Molecular Weight
Mass (kDA):
46.154 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.1 |
| Sequence: | 17; NC_000017.11 (7572825..7579006) |
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Malignant Neoplasm Of Lung
- Cytomegalovirus Infections
- Dental Plaque
- Liver Regeneration Disorder
- Lung Neoplasms
- Non-small Cell Lung Carcinoma
- Stage I Non-small Cell Lung Cancer
- Neurodegenerative Disorders
- Tdp-43 Proteinopathies
Interacting Proteins
- EIF4G1
- EIF4G2
- EIF4H
- PDCD4
Pathways
- Translation
- Localization
- Methylation
- Regulation Of Translation
- Cell Adhesion
- Transport
- Cell Proliferation
- Fertilization
- Hepatocyte Proliferation
- Conjugation
- Nuclear Export
- Regeneration
PTMs
- Phosphorylation
Research Areas
- Core ESC-Like Genes
- mTOR Pathway
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF4A1
bosterbio.com/bosterbio-gene-info-cards/EIF4A1
References
PMID: 8493113 by Kim N.-S., et al. Nucleotide sequence of human cDNA encoding eukaryotic initiation factor 4AI.
PMID: 9548260 by Craig A.W.B., et al. Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation.