EIF4G1 Antibodies

AND EIF4G1 ELISA kits, EIF4G1 Proteins

Many biological assays use antibodies to detect EIF4G1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF4G1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF4G1 antibodies...

We validate the specificity of these antibodies to EIF4G1 by testing them on tissues known to express EIF4G1 positively and negatively. Browse below to find the EIF4G1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for EIF4G1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the EIF4G1 IHC Guide

EIF4G1 Infographic by Boster Bio

All EIF4G1 Products

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Anti-EIF4G1 Antibody Picoband®

IHC analysis of EIF4G1 using anti-EIF4G1 antibody (A01351-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01351-2
100 μg/vial

EIF4G1 (NM_004953) Human Over-expression Lysate

EIF4G1 Human Over-expression Lysates NM_004953

Human

$960
Cat # LS001981
20 µg, 100 µg

EIF4G1 Overview

Facts about Eukaryotic translation initiation factor 4 gamma 1.

EIF4G1 3D structure. Source: alphafold

Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1)

Part of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. .

Gene Information

Human
Gene Name:	EIF4G1
Uniprot:	Q04637
Entrez:	1981

Family

Belongs to:

eukaryotic initiation factor 4G family

Alternative Names

DKFZp686A1451; EIF4F; eIF-4G 1; eIF4G1; EIF-4G1; eIF-4-gamma 1; EIF4-gamma; EIF4GI; EIF4Gp220; eucaryotic translation initiation factor 4G; eukaryotic translation initiation factor 4 gamma 1; eukaryotic translation initiation factor 4 gamma, 1; P220

Molecular Weight

Mass (kDA):
175.491 kDA

Genomic Context


Human

Location:	3q27.1
Sequence:	3; NC_000003.12 (184314495..184335358)

Diseases

Neoplasms
Malignant Neoplasms
Parkinson Disease
Foot-and-mouth Disease
Carcinoma
Malignant Paraganglionic Neoplasm
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Immunologic Deficiency Syndromes
Secondary Parkinson Disease
Cell Invasion
Picornaviridae Infections

Mammary Neoplasms
Malignant Squamous Cell Neoplasm
Virus Diseases
Hiv Infections
Lymphoma
Infective Disorder

Interacting Proteins

DDX3X
EIF3J
EIF4A1
EIF4E
PABPC1

Pathways

Translation
Cell Death
Cell Cycle
Localization
Pathogenesis
Cell Growth
Proteolysis
Regulation Of Translation
Cell Proliferation
Rna Interference
Transport
Gene Silencing
Induction Of Apoptosis

Angiogenesis
Autophagy
Protein Phosphorylation
Cell Activation
Cell Migration
Programmed Cell Death
T Cell Activation

PTMs

Cleavage
Phosphorylation
Dephosphorylation

Farnesylation
Citrullination
Methylation

Research Areas

Cancer
DNA Repair
DNA replication, Transcription, Translation and Splicing
mTOR Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF4G1

References

PMID: 1429670 by Yan R., et al. Amino acid sequence of the human protein synthesis initiation factor eIF-4 gamma.

PMID: 9857202 by Imataka H., et al. A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation.