This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
Neutrophil elastase Antibodies
AND ELANE ELISA kits, Neutrophil elastase Proteins
Many biological assays use antibodies to detect Neutrophil elastase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neutrophil elastase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neutrophil elastase antibodies...
Previous: CCN2
Next: SERPINB1
ELANE Infographic by Boster Bio
All ELANE Products
Product
Figures
Specificity
Applications
Price
Mouse Neutrophil Elastase/ELA2/ELANE ELISA Kit PicoKine®
1 Citations 7 Q&As
Mouse
ELISA
$499
Cat # EK1445
96 wells/kit, with removable strips.
Cat # EK1445
96 wells/kit, with removable strips.
Mouse, Rat
IHC, WB
$370
Cat # PB10058
100 μg/vial
Cat # PB10058
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01607
100 μl
Cat # M01607
100 μl
Human Neutrophil Elastase/ELA2/ELANE ELISA Kit PicoKine®
4 Citations 7 Q&As
Human
ELISA
$499
Cat # EK2064
96 wells/kit, with removable strips.
Cat # EK2064
96 wells/kit, with removable strips.
Human
Flow Cytometry, IF, IHC, ICC, WB
$405
Cat # A01607-1
100ul
Cat # A01607-1
100ul
ELANE Overview
Facts about Neutrophil elastase.
Neutrophil elastase (ELANE)
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ELANE |
| Uniprot: | P08246 |
| Entrez: | 1991 |
Family
| Belongs to: |
|---|
| peptidase S1 family |
Alternative Names
Bone marrow serine protease; EC 3.4.21; EC 3.4.21.37; ELA2; ELA2granulocyte-derived elastase; ELANE; elastase 2, neutrophil; elastase, neutrophil expressed; Elastase-2; GE; HLEelastase-2; HNE; Human leukocyte elastase; Leukocyte Elastase; Medullasin; NE; Neutrophil Elastase; PMN elastase; PMN-E; polymorphonuclear elastase; SCN1
Molecular Weight
Mass (kDA):
28.518 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (850997..856250) |
Tissue Specificity
Bone marrow cells.
Subcellular Localizations
Cytoplasmic vesicle, phagosome. Localized in phagolysosomes following ingestion of E.coli by neutrophils.
Diseases
- Severe Congenital Neutropenia
- Leukemia
- Cyclic Neutropenia
- Infective Disorder
- Bacterial Infections
- Growth Arrest
- Neutropenia Chronic
- Malignant Paraganglionic Neoplasm
- Lung Diseases
- Pancytopenia
- Immunologic Deficiency Syndromes
- Malignant Neoplasms
Interacting Proteins
- Col17a1
Pathways
- Pathogenesis
- Cell Proliferation
- Proteolysis
- Wound Healing
- Neutrophil Activation
PTMs
- Disulfide bond
Research Areas
- Cancer
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ELANE
bosterbio.com/bosterbio-gene-info-cards/ELANE
References
PMID: 3479752 by Nakamura H., et al. Nucleotide sequence of human bone marrow serine protease (medullasin) gene.
PMID: 2902087 by Takahashi H., et al. Structure of the human neutrophil elastase gene.
5 Publications of Boster Neutrophil elastase Antibodies & ELISA Kits
- PubMed ID: 10.1186/s13568-016-0212-1, The Burkholderia cenocepacia OmpA-like protein BCAL2958: identification, charact...
- PubMed ID: 10.1177/0963689719874048, Endothelial Progenitor Cells Attenuate Ventilator-Induced Lung Injury with Large...
- PubMed ID: 10.1155/2019/7142438, Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Brea...
- PubMed ID: 10.1016/j.cellsig.2021.110168, Mechanism of neutrophil extracellular traps generation and their role in trophob...
- PubMed ID: 27325348, The Burkholderia cenocepacia OmpA-like protein BCAL2958: identification, charact...
*More publications can be found for each product on its corresponding product page