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Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
|Sequence:||6; NC_000006.12 (53267398..53349179, complement)|
Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree.