Emerin Antibodies

Emerin (EMD)

Stabilizes and promotes the creation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments.

Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by changing the nuclear accumulation of beta- catenin through a CRM1-dependent export pathway.

Gene Information

Human
Gene Name:	EMD
Uniprot:	P50402
Entrez:	2010

Family

Belongs to:
No superfamily

Alternative Names

emerin; Emery-Dreifuss muscular dystrophy; LEM domain containing 5; STAEDMDLEMD5

Molecular Weight

Mass (kDA):
28.994 kDA

Genomic Context

Human
Location:	Xq28
Sequence:	X; NC_000023.11 (154379236..154381523)

Tissue Specificity

Skeletal muscle, heart, colon, testis, ovary and pancreas.

Subcellular Localizations

Nucleus inner membrane; Single-pass membrane protein; Nucleoplasmic side. Nucleus outer membrane. Colocalized with BANF1 at the central region of the assembling nuclear rim, near spindle-attachment sites. The accumulation of different intermediates of prelamin-A/C (non-farnesylated or carboxymethylated farnesylated prelamin-A/C) in fibroblasts modify its localization in the nucleus.

Diseases

• Alveolar Bone Loss
• Gingival Recession
• Periodontal Attachment Loss
• Periodontal Pocket
• Periodontitis
• Neoplasms
• Cardiac Arrest
• Hemorrhage
• Chronic Periodontitis
• Dental Plaque
• Malignant Neoplasms
• Pain
• Electromechanical Dissociation

• Cardiac Fibrillation
• Cardiac Arrhythmia
• Heart Failure
• Ventricular Fibrillation
• Periodontal Diseases
• Tissue Adhesions
• Muscle Twitch

Interacting Proteins

• ABT1
• ACTB
• AEN
• BANF1
• BCLAF1

• BYSL
• CATSPER1
• CCDC155
• CEP70
• CTNNB1

• EFHC2
• FATE1
• LUZP4
• MAB21L3
• MEOX2

• PAK5
• SH3GL2
• STX4
• Sun1
• SUN2

• TRAF3IP3
• TRIM42
• VAPB
• ZFP64
• ZNF165

• ZNF232

Pathways

• Regeneration
• Tissue Regeneration
• Wound Healing
• Cell Proliferation
• Transport
• Secretion
• Sensitization
• Angiogenesis
• Cell Growth
• Localization
• Cell Differentiation
• Cell Adhesion
• Reflex

• Muscle Contraction
• Cell Cycle
• Pathogenesis
• Cell Migration
• Osteoblast Differentiation
• Inflammatory Response
• Dehiscence

PTMs

• Phosphorylation
• Cleavage
• Reduction
• Oxidation
• Demethylation

• Hydroxylation
• Deiodination
• Dephosphorylation
• Nitration
• Glycosylation

• Bromination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EMD

Boster Bio Antibodies - Best Uses Of The EMD Marker

You might be interested by Anti-Fibronectin Fn1 Monoclonal Antibodies produced by Boster Bio Anti-POU5F1 as well as Anti-Fibronectin Fn1 Monoclonal Antibodies. But which one is best for your needs? This article will discuss the differences between these two products and will also go over their best uses. You can also learn more about Boster Bio's ICVA or ICC.

Boster Bio Anti-POU5F1 Antibody

Boster Bio AntipOU5F1, # A00174-1 is a reaction between human GTPase (GTPase) and the protein CD235a. It's non-hazardous and may be purchased in 10 mM of PBS with either 0.05 percent BSA or 0.01% zide. If you'd like to use this antibody for a WB or IHC assay, it is recommended to purchase a blocking peptide, that can be purchased separately. This peptide, along with Boster Bio Antibodies POU5F1, is validated on WB immunofluorescence, and ELISA.

Boster Bio Anti-Fibronectin Fn1 Monoclonal Antibody

Boster Bio Antifibronectin FN1 Monoclonal Antibody biotin-conjugated, anti-biotin antibody. This antibody reacts with mouse and human ECM and cell surface cells. It is compatible with positive and negative samples, which makes it an the ideal tool for research in the field of musculoskeletal diseases.

The most popular compositions of antibodies are monoclonal or polyclonal antibody that bind the CT protein or polypeptide. Monoclonal and monoclonal antibodies work best, however polyclonal antibodies can also be useful. The preferred antibody compositions are derived by immunizing animals with CT and choosing the most specific among them.

The polypeptide used in the production of antibodies is referred to as the inoculum. The protein is a polymer . It is able to be prepared in isolation or in conjunction with the carrier in a conjugate. The conjugate is more potent than monoclonal antibodies. The polypeptide may also be used as a biomarker to monitor disease progression or to monitor patient responses to therapy.

Boster Bio's EMD Marker

Boster Bio's EMD Marker was created using monoclonal high affinity antibody to detect the Olfactory Marker protein in rat, mouse and human samples. These antibodies are well known and have been extensively verified by the research community. Boster Bio's antibodies are used in many different tissues and are extremely specific and reactive. This product is ideal for both research and diagnostic purposes.

ICC

Boster Bio's products are among the best for EMD markers. These high-affinity primary antibodies have been extensively cited over the last 25 years and have been validated for use in Western Blotting, Immunohistochemistry, and ELISA. The products they make are designed to ensure the highest performance So you can be at ease knowing that they work exactly as they say.

Immunofluorescence

Boster Bio has announced the appointment of LAB-APORTER Limited as the official distributor for its EMD markers. The company provides customers with the antibodies, ELISA kits, and technical support needed to achieve their research goals. Boster Bio has been manufacturing high-quality antibodies and ELISA kits since 1993. All of Boster's products undergo rigorous validation and quality control to ensure high quality and high productivity.

The EMD marker is an EMD-specific protein that recognizes many human cell surface antigens. The antibodies used in this procedure can be fluorescent or not conjugated. The fluorophore-conjugated antibodies are particularly useful because they eliminate the possibility of non-specific binding. Secondary antibodies that fail to penetrate the cells can result in non-specific binding. Fortunately that the Boster Bio EMD markers are widely available, enabling researchers to identify thousands of targets.