EPHX2 Antibodies

AND EPHX2 ELISA kits, EPHX2 Proteins

Many biological assays use antibodies to detect EPHX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EPHX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EPHX2 antibodies...

We validate the specificity of these antibodies to EPHX2 by testing them on tissues known to express EPHX2 positively and negatively. Browse below to find the EPHX2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for EPHX2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the EPHX2 Western Blot Guide

EPHX2 Infographic by Boster Bio

All EPHX2 Products

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Specificity

Applications

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Anti-EPHX2 Antibody Picoband®

Flow Cytometry analysis of PC-3 cells using anti-EPHX2 antibody (A01999-1)

Western blot analysis of EPHX2 using anti-EPHX2 antibody (A01999-1)

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # A01999-1
100 μg/vial

Anti-EPHX2 Rabbit Monoclonal Antibody

Western blot analysis of EPHX2 expression in MCF7 cell lysate

Human

$370
Cat # M01999-3
100 μl/vial

EPHX2 Overview

Facts about Bifunctional epoxide hydrolase 2.

EPHX2 3D structure. Source: alphafold

Bifunctional epoxide hydrolase 2 (EPHX2)

Bifunctional enzyme (PubMed:12574510). The C-terminal domain has epoxide hydrolase activity and functions on epoxides (alkene oxides, oxiranes) and arene oxides (PubMed:12869654, PubMed:12574510, PubMed:22798687).

Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Additionally determines steady-state levels of physiological mediators (PubMed:12869654, PubMed:12574510, PubMed:22798687).

Gene Information

Human
Gene Name:	EPHX2
Uniprot:	P34913
Entrez:	2053

Family

Belongs to:

AB hydrolase superfamily

Alternative Names

Bifunctional Epoxide Hydrolase 2; CEH; Cytosolic epoxide hydrolase; EC 3.3.2.10; EPHX2; Epoxide Hydratase 2; Epoxide hydratase; Epoxide Hydrolase 2; epoxide hydrolase 2, cytoplasmic; Epoxide Hydrolase 2, Cytosolic; epoxide hydrolase, soluble; SEH; Soluble epoxide hydrolase

Molecular Weight

Mass (kDA):
62.616 kDA

Genomic Context


Human

Location:	8p21.2-p21.1
Sequence:	8; NC_000008.11 (27491143..27597559)

Subcellular Localizations

Cytoplasm. Peroxisome.

Diseases

Cardiovascular Diseases
Hypertensive Disease
Inflammation
Ischemia
Cerebrovascular Accident
Malignant Neoplasms
Neoplasms
Atherosclerosis
Brain Ischemia
Heart Diseases
Ischemic Stroke
Tumor Angiogenesis
Infarction

Carcinogenesis
Hypertrophy
Myocardial Ischemia
Coronary Heart Disease
Diabetes Mellitus
Myocardial Reperfusion Injury
Coronary Artery Disease

Pathways

Pathogenesis
Cell Death
Angiogenesis
Excretion
Cell Proliferation
Methylation
Transport
Dna Methylation
Localization
Inflammatory Response
Glucose Homeostasis
Cell Cycle
Demethylation

Cell Growth
Rna Interference
Secretion
Muscle Cell Proliferation
Dna Demethylation
Tube Formation
Smooth Muscle Cell Proliferation

PTMs

Phosphorylation
Methylation

Demethylation
Cleavage

Oxidation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EPHX2

References

PMID: 8342951 by Beetham J.K., et al. cDNA cloning and expression of a soluble epoxide hydrolase from human liver.

PMID: 8619856 by Sandberg M., et al. Structural characterization of the human soluble epoxide hydrolase gene (EPHX2).