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- Table of Contents
Erythropoietin receptor Antibodies
AND EPOR ELISA kits, Erythropoietin receptor Proteins
Many biological assays use antibodies to detect Erythropoietin receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Erythropoietin receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Erythropoietin receptor antibodies...
Designing a Western blot for Erythropoietin receptor? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the EPOR Western Blot GuideEPOR Infographic by Boster Bio
All EPOR Products
Product
Figures
Specificity
Applications
Price
Anti-EPO Receptor/EPOR Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, WB
$370
Cat # A00427-1
100 μg/vial
Cat # A00427-1
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00427-1
100 μg
Cat # M00427-1
100 μg
Human, Mouse, Rat
ELISA
$540
Cat # EKC2255
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2255
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1197
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1197
1 kit, containing one 96-well plate and all necessary reagents
EPOR Overview
Facts about Erythropoietin receptor.
Erythropoietin receptor (EPOR)
Receptor for erythropoietin.
Mediates erythropoietin- induced erythroblast proliferation and differentiation.Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3.
Gene Information
| Human | |
|---|---|
| Gene Name: | EPOR |
| Uniprot: | P19235 |
| Entrez: | 2057 |
Family
| Belongs to: |
|---|
| type I cytokine receptor family |
Alternative Names
EpoR; EPO-R; Erythropoietin R; erythropoietin receptor; MGC138358
Molecular Weight
Mass (kDA):
55.065 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.2 |
| Sequence: | 19; NC_000019.10 (11377207..11384314, complement) |
Tissue Specificity
Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EPOR-T is the most abundant from in early- stage erythroid progenitor cells.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.; [Isoform EPOR-S]: Secreted. Secreted and located to the cell surface.
Diseases
- Anemia
- Neoplasms
- Hypoxia
- Malignant Neoplasms
- Polycythemia
- Acute Erythroblastic Leukemia
- Tumor Angiogenesis
- Leukemia
- Ischemia
- Carcinoma
- Erythrocytosis
- Polycythemia Vera
- Cerebrovascular Accident
Interacting Proteins
- ATXN2L
- Cish
- EPO
- PLCG2
- PTPN1
- PTPN6
- SOCS2
Pathways
- Cell Proliferation
- Angiogenesis
- Neuroprotection
- Pathogenesis
- Cell Death
- Cell Growth
- Secretion
- Hypersensitivity
- Reverse Transcription
- Cell Cycle
- Transport
- Neurogenesis
- Cell Differentiation
PTMs
- Phosphorylation
- Glycosylation
- Carbamylation
- Dephosphorylation
Research Areas
- Angiogenesis
- Immunology
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EPOR
bosterbio.com/bosterbio-gene-info-cards/EPOR
References
PMID: 2163695 by Winkelmann J.C., et al. The gene for the human erythropoietin receptor: analysis of the coding sequence and assignment to chromosome 19p.
PMID: 2163696 by Jones S.S., et al. Human erythropoietin receptor: cloning, expression, and biologic characterization.
1 Publications of Boster Erythropoietin receptor Antibodies & ELISA Kits
- PubMed ID: 21339183, Gao Y, Mengana Y, Cruz Yr, Mu??oz A, Test?? Is, Garc??a Jd, Wu Y, Rodr??guez Jc,...
*More publications can be found for each product on its corresponding product page