Endoplasmic reticulum aminopeptidase 2 (ERAP2)

Aminopeptidase that plays a central role in peptide trimming, a measure required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them into the right length required for presentation on MHC class I molecules.

Preferentially hydrolyzes the basic residues Arg and Lys. .