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- Table of Contents
Proepiregulin Antibodies
AND EREG ELISA kits, Proepiregulin Proteins
Many biological assays use antibodies to detect Proepiregulin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Proepiregulin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Proepiregulin antibodies...
Designing a Western blot for Proepiregulin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the EREG Western Blot GuideEREG Infographic by Boster Bio
All EREG Products
Product
Figures
Specificity
Applications
Price
Human Epiregulin ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK1394
96 wells/kit, with removable strips.
Cat # EK1394
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1395
96 wells/kit, with removable strips.
Cat # EK1395
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A06692-2
100 μg/vial
Cat # A06692-2
100 μg/vial
Monkey
ELISA
$499
Cat # EK1394-PR
96 wells/kit, with removable strips.
Cat # EK1394-PR
96 wells/kit, with removable strips.
Pig
ELISA
$499
Cat # EK1394-PO
96 wells/kit, with removable strips.
Cat # EK1394-PO
96 wells/kit, with removable strips.
EREG Overview
Facts about Proepiregulin.
Proepiregulin (EREG)
Ligand of the EGF receptor/EGFR and ERBB4.
Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975).Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357). .
Gene Information
| Human | |
|---|---|
| Gene Name: | EREG |
| Uniprot: | O14944 |
| Entrez: | 2069 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Epiregulin; ER; EREG; proepiregulin
Molecular Weight
Mass (kDA):
19.044 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q13.3 |
| Sequence: | 4; NC_000004.12 (74365145..74388749) |
Subcellular Localizations
[Epiregulin]: Secreted, extracellular space.; [Proepiregulin]: Cell membrane; Single-pass type I membrane protein.
Diseases
- Neoplasms
- Malignant Neoplasms
- Colorectal Cancer
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Colorectal Neoplasms
- Mammary Neoplasms
- Colorectal Cancer Metastatic
- Carcinoma
- Hyperplasia
- Neoplasm Invasiveness
- Cell Transformation, Neoplastic
Pathways
- Ovulation
- Oocyte Maturation
- Pathogenesis
- Cell Proliferation
- Luteinization
- Metaphase
- Gene Silencing
- Immune Response
- Cell Cycle
- Methylation
- Cell Growth
- Rna Interference
- Cell Differentiation
PTMs
- Phosphorylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EREG
bosterbio.com/bosterbio-gene-info-cards/EREG
References
PMID: 9337852 by Toyoda H., et al. Distribution of mRNA for human epiregulin, a differentially expressed member of the epidermal growth factor family.
PMID: 9419975 by Komurasaki T., et al. Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4.