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- Table of Contents
Facts about Serine/threonine-protein kinase/endoribonuclease IRE2.
Appears to play no part in the unfolded-protein reply, unlike closely related proteins. .
| Human | |
|---|---|
| Gene Name: | ERN2 |
| Uniprot: | Q76MJ5 |
| Entrez: | 10595 |

| Belongs to: |
|---|
| protein kinase superfamily |

EC 2.7.11; endoplasmic reticulum to nucleus signaling 2; endoplasmic reticulum to nucleus signalling 2; Endoplasmic reticulum-to-nucleus signaling 2; ER to nucleus signalling 2; hIRE2p; inositol-requiring 1 beta; Inositol-requiring protein 2; IRE1, S. cerevisiae, homolog of; Ire1-beta; IRE1bIRE1 beta; IRE2; serine/threonine-protein kinase/endoribonuclease IRE2
Mass (kDA):
102.48 kDA

| Human | |
|---|---|
| Location: | 16p12.2 |
| Sequence: | 16; NC_000016.10 (23690310..23713248, complement) |
Endoplasmic reticulum membrane; Single-pass type I membrane protein.




PMID: 11175748 by Iwawaki T., et al. Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress.