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|Sequence:||1; NC_000001.11 (236213064..236281983, complement)|
Highly expressed in the digestive tract, including the duodenum and lower digestive tract. In the stomach, highly expressed in enzyme-producing chief cells (at protein level). In the pancreas, expressed in islets of Langerhans and, at lower levels, in enzyme-secreting cells (at protein level). Detected at low level in many other tissues.
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. The association with ERP44 may be essential for its retention in the endoplasmic reticulum.