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Inhibits EGFR catalytic activity by interfering with its dimerization. Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4.
|Sequence:||1; NC_000001.11 (8011725..8026309, complement)|
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Associated with the plasma membrane of basal skin keratinocytes. Translocates into the nucleus of differentiating suprabasal keratinocytes (By similarity).