Transcription factor ETV6 Antibodies

AND ETV6 ELISA kits, Transcription factor ETV6 Proteins

Many biological assays use antibodies to detect Transcription factor ETV6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor ETV6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor ETV6 antibodies...

We validate the specificity of these antibodies to Transcription factor ETV6 by testing them on tissues known to express ETV6 positively and negatively. Browse below to find the ETV6 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ETV6 Infographic by Boster Bio

All ETV6 Products

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Anti-TEL ETV6 Antibody

7 Q&As

Western Blot analysis of various cells using TEL Polyclonal Antibody

Western blot analysis of lysates from HeLa, HepG2, and Jurkat cells, using ETV6 Antibody

Immunohistochemical analysis of paraffin-embedded human Colon cancer

Human, Mouse, Rat

ELISA, IF, IHC, WB

$399
Cat # A00361
100μl

Anti-ETV6/Tel Antibody Picoband®

1 Q&As

Western blot analysis of ETV6/Tel using anti-ETV6/Tel antibody (A00361-1)

IHC analysis of ETV6/Tel using anti-ETV6/Tel antibody (A00361-1)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A00361-1
100 μg/vial

ETV6 Colorimetric Cell-Based ELISA

Western blot analysis of extracts from HeLa/HepG2/Jurkat cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1718
1 kit, containing one 96-well plate and all necessary reagents

Anti-ETV6 Antibody (N-term)

ETV6 Antibody (N-term) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # A00361-2
80 µl

Anti-ETV6 Rabbit Monoclonal Antibody

Western blot analysis of ETV6 expression in A431 cell lysate

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # M00361
100 μl/vial

ETV6 (NM_001987) Human Over-expression Lysate

Human

$628
Cat # LS002120
20 µg, 100 µg

ETV6 Overview

Facts about Transcription factor ETV6.

ETV6 3D structure. Source: alphafold

Transcription factor ETV6 (ETV6)

Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.

Gene Information

Human
Gene Name:	ETV6
Uniprot:	P41212
Entrez:	2120

Family

Belongs to:

ETS family

Alternative Names

ETS translocation variant 6; ets variant 6; ets variant gene 6 (TEL oncogene); ETS-related protein Tel1; ETV6; TEL; TEL/ABL; TEL1; TELTEL1 oncogene; transcription factor ETV6

Molecular Weight

Mass (kDA):
53 kDA

Genomic Context


Human

Location:	12p13.2
Sequence:	12; NC_000012.12 (11649601..11895386)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus.

Diseases

Leukemia
Acute Lymphocytic Leukemia
Malignant Neoplasms
Chromosomal Translocation
Neoplasms
Myeloid Leukemia
Leukemia, Myelocytic, Acute
L1 Acute Lymphoblastic Leukemia
Cytogenetic Abnormality
Hematologic Neoplasms
Leukemogenesis
Dysmyelopoietic Syndromes

Malignant Paraganglionic Neoplasm
Precursor B-cell Lymphoblastic Leukemia-lymphoma
Cell Transformation, Neoplastic
Carcinoma
Myeloid Leukemia, Chronic
Myeloproliferative Disease
Precursor T-cell Lymphoblastic Leukemia-lymphoma

Interacting Proteins

AP1M1
WDYHV1

Pathways

Pathogenesis
Interphase
Metaphase
Localization
Cell Cycle
Reverse Transcription
Methylation
Oncogenesis
Cell Proliferation
Cell Differentiation
Nuclear Export
Cell Cycle Arrest
Translation

Induction Of Apoptosis
Drug Resistance
Cell Growth
Angiogenesis
Response To Wounding
Gene Silencing
Immune Response

PTMs

Phosphorylation
Methylation
Sumoylation

Cleavage
Ubiquitination
Phosphorothioation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ETV6

References

PMID: 8168137 by Golub T.R., et al. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation.

PMID: 8743990 by Baens M., et al. Genomic organization of TEL: the human ETS-variant gene 6.