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- Table of Contents
Ecsit Antibodies
AND Ecsit ELISA kits, Ecsit Proteins
Many biological assays use antibodies to detect Ecsit, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ecsit in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ecsit antibodies...
Designing a Western blot for Ecsit? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ECSIT Western Blot GuideEcsit Infographic by Boster Bio
All Ecsit Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A07966-3
100 μg/vial
Cat # A07966-3
100 μg/vial
Ecsit Overview
Facts about Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial.
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Ecsit)
Adapter protein of this Toll-like and IL-1 receptor signaling pathway that is involved in the regeneration of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1.
Involved in the BMP signaling pathway. Required for normal embryonic development.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Ecsit |
| Uniprot: | Q9QZH6 |
| Entrez: | 26940 |
Family
| Belongs to: |
|---|
| ECSIT family |
Alternative Names
ECSIT homolog (Drosophila); evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; likely ortholog of mouse signaling intermediate in Toll pathway evolutionarilyconserved; Protein SITPEC; signaling intermediate in Toll pathway evolutionarily conserved ortholog; SITPECsignaling intermediate in Toll pathway, evolutionarily conserved
Molecular Weight
Mass (kDA):
49.799 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 9|9 A3 |
| Sequence: | 9; |
Tissue Specificity
Detected in heart, brain, lung, liver, skeletal muscle, kidney and testis. Detected in embryonic mesoderm and epiblast, and in extraembryonic ectoderm.
Diseases
- Innate Immune Response
- Inflammation
- Alzheimer's Disease
- Hereditary Diseases
- Syncope
- Pulpitis
- Iron Overload
- Hereditary Hemochromatosis
- Mitochondrial Damage
- Inflammatory Response
- Blind Vision
- Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
Pathways
- Oxidative Phosphorylation
- Pathogenesis
- Transport
- Cell Proliferation
- Immune Response
- Mesoderm Formation
- Localization
- Bmp Signaling Pathway
- Inflammatory Response
- Cell Differentiation
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Immunology
- Innate Immunity
- Signal Transduction
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ecsit
bosterbio.com/bosterbio-gene-info-cards/Ecsit
References
PMID: 10465784 by Kopp E., et al. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.
PMID: 14633973 by Xiao C., et al. Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.