Product Info Summary
SKU: | A09208 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-FAM120A Antibody
SKU/Catalog Number
A09208
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-FAM120A Antibody (Catalog # A09208). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
FAM120A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-FAM120A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09208)
Host
Rabbit
Contents
FAM120A Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
SK7
Isotype
IgG
Immunogen
FAM120A antibody was raised against an 18 amino acid synthetic peptide from near the center of human FAM120A. The immunogen is located within amino acids 610 - 660 of FAM120A.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody will not cross-reacti with FAM120B / PGCC1.
Reactive Species
A09208 is reactive to FAM120A in Human, Mouse, Rat
Applications
A09208 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
121.888kDa
Background of FAM120A
FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FAM120A antibody can be used for detection of FAM120A by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of FAM120A in SK-N-SH cell lysate with FAM120A antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemistry of FAM120A in rat brain tissue with FAM120A antibody at 2.5 μg/mL.
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Immunofluorescence of FAM120A in Rat Brain cells with FAM120A antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For FAM120A (Source: Uniprot.org, NCBI)
Gene Name
FAM120A
Full Name
Constitutive coactivator of PPAR-gamma-like protein 1
Weight
121.888kDa
Superfamily
constitutive coactivator of PPAR-gamma family
Alternative Names
C9orf10MGC133257; chromosome 9 open reading frame 10; constitutive coactivator of PPAR-gamma-like protein 1; DNA polymerase-transactivated protein 1; DNA polymerase-transactivated protein 5; DNAPTP1; DNAPTP5; family with sequence similarity 120A; KIAA0183MGC111527; OSSA; Oxidative stress-associated Src activator; Protein FAM120A FAM120A C9orf10, HBVPTPAP, OSSA family with sequence similarity 120A constitutive coactivator of PPAR-gamma-like protein 1|oxidative stess-associated Src activator|oxidative stress-associated Src activator
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FAM120A, check out the FAM120A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FAM120A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FAM120A Antibody (A09208)
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No publications found for A09208
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