Anti-FAM120A Antibody

Product Name

Anti-FAM120A Antibody

View all FAM120A Antibodies

SKU/Catalog Number

A09208

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-FAM120A Antibody (Catalog # A09208). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

FAM120A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-FAM120A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09208)

Host

Rabbit

Contents

FAM120A Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

FAM120A antibody was raised against an 18 amino acid synthetic peptide from near the center of human FAM120A. The immunogen is located within amino acids 610 - 660 of FAM120A.

Cross-reactivity

This antibody will not cross-reacti with FAM120B / PGCC1.

Reactive Species

A09208 is reactive to FAM120A in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

121.9 kDa

Background of FAM120A

FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A09208 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

FAM120A antibody can be used for detection of FAM120A by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information FAM120A

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