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- Table of Contents
FCGR2A Antibodies
AND FCGR2A ELISA kits, FCGR2A Proteins
Many biological assays use antibodies to detect FCGR2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FCGR2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FCGR2A antibodies...
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FCGR2A Infographic by Boster Bio
All FCGR2A Products
Product
Figures
Specificity
Applications
Price
Anti-FCGR2A Antibody Picoband®
2 Citations 1 Q&As
Human, Mouse, Rat
IHC, WB, ELISA (Cap)
$370
Cat # A01450-1
100 μg/vial
Cat # A01450-1
100 μg/vial
Human
IP, IF, IHC, WB
$523
Cat # M01450-1
100 µl
Cat # M01450-1
100 µl
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01450-3
100 μg
Cat # M01450-3
100 μg
FCGR2A Overview
Facts about Low affinity immunoglobulin gamma Fc region receptor II-a.
Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A)
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor.
By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Gene Information
| Human | |
|---|---|
| Gene Name: | FCGR2A |
| Uniprot: | P12318 |
| Entrez: | 2212 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD32 antigen; CD32a; CD32MGC23887; CDw32fc-gamma-RIIa; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc gamma RIIA; FCG2; Fc-gamma RII-a; Fc-gamma-RIIa; FcGR; FCGR2; FCGR2A; FCGR2A1; FcgRIIA; FCRIIA; fcRII-a; IGFR2MGC30032; IgG Fc receptor II-a; Immunoglobulin G Fc receptor II; low affinity immunoglobulin gamma Fc region receptor II-a
Molecular Weight
Mass (kDA):
35.001 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q23.3 |
| Sequence: | 1; NC_000001.11 (161505430..161524048) |
Tissue Specificity
Found on monocytes, neutrophils and eosinophil platelets.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Lupus Erythematosus, Systemic
- Autoimmune Reaction
- Autoimmune Diseases
- Arthritis
- Rheumatoid Arthritis
- Inflammation
- Dysequilibrium Syndrome
- Malignant Neoplasms
- Malaria
- Malaria, Falciparum
- Infective Disorder
- Autoimmunity
- Lymphoma
Interacting Proteins
- UBQLN1
Pathways
- Pathogenesis
- Immune Response
- Phagocytosis
- Antibody-dependent Cellular Cytotoxicity
- Platelet Activation
- Secretion
- Inflammatory Response
- Platelet Aggregation
- Cell Activation
- Complement Activation
- Respiratory Burst
- Virulence
- Mast Cell Activation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCGR2A
bosterbio.com/bosterbio-gene-info-cards/FCGR2A
References
PMID: 2824655 by Stuart S.G., et al. Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII).
PMID: 2529342 by Brooks D.G., et al. Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes.
1 Publications of Boster FCGR2A Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.jaut.2017.09.002, Myelin oligodendrocyte glycoprotein-specific antibodies from multiple sclerosis ...
*More publications can be found for each product on its corresponding product page