FCHO2 Antibodies

AND FCHO2 ELISA kits, FCHO2 Proteins

Many biological assays use antibodies to detect FCHO2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FCHO2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FCHO2 antibodies...

We validate the specificity of these antibodies to FCHO2 by testing them on tissues known to express FCHO2 positively and negatively. Browse below to find the FCHO2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FCHO2 Infographic by Boster Bio

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Anti-F-BAR domain only protein 2 FCHO2 Antibody

Western blot analysis of FCHO2 in rat heart tissue lysate with FCHO2 antibody at (A) 1 and (B) 2 μg/ml

Immunohistochemistry of FCHO2 in human heart tissue with FCHO2 antibody at 2

Immunofluorescence of FCHO2 in human heart tissue with FCHO2 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A08075
0.1 mg

FCHO2 Overview

Facts about F-BAR domain only protein 2.

FCHO2 3D structure. Source: alphafold

F-BAR domain only protein 2 (FCHO2)

Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the capacity to recruit proteins essential to the formation of functional clathrin-coated pits.

Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) such as the plasma membrane. Its membrane-bending activity might be important for the subsequent actions of clathrin and adaptors in the formation of clathrin-coated vesicles.

Gene Information

Human
Gene Name:	FCHO2
Uniprot:	Q0JRZ9
Entrez:	115548

Family

Belongs to:

FCHO family

Alternative Names

FCH domain only 2

Molecular Weight

Mass (kDA):
88.924 kDA

Genomic Context


Human

Location:	5q13.2
Sequence:	5; NC_000005.10 (72956041..73090522)

Subcellular Localizations

Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side. Associated with forming but not mature clathrin-coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2 (By similarity).