FCRL4 Antibodies

AND FCRL4 ELISA kits, FCRL4 Proteins

Many biological assays use antibodies to detect FCRL4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FCRL4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FCRL4 antibodies...

We validate the specificity of these antibodies to FCRL4 by testing them on tissues known to express FCRL4 positively and negatively. Browse below to find the FCRL4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FCRL4 Infographic by Boster Bio

All FCRL4 Products

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Product

Figures

Specificity

Applications

Price

Anti-Fc receptor-like protein 4 FCRL4 Antibody

Western blot analysis of extracts of various cell lines, using FCRL4 antibody at 1:1000 dilution

Human, Mouse, Rat

IHC, WB

$405
Cat # A05956
100ul

Anti-FCRL4 Antibody (C-term)

All lanes : Anti-FCRL4 Antibody (C-term) at 1:2000 dilutionLane 1: 293T/17 whole cell lysateLane 2: Ramos whole cell lysateLane 3: Raji whole cell lysateLane 4: Daudi whole cell lysateLysates/proteins at 20 µg per lane

Human

Flow Cytometry, WB

$299
Cat # A05956-1
80 µl

FCRL4 (NM_031282) Human Over-expression Lysate

Human

$960
Cat # LS083417
20 µg, 100 µg

FCRL4 Overview

Facts about Fc receptor-like protein 4.

FCRL4 3D structure. Source: alphafold

Fc receptor-like protein 4 (FCRL4)

May be an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response.

Gene Information

Human
Gene Name:	FCRL4
Uniprot:	Q96PJ5
Entrez:	83417

Family

Belongs to:

No superfamily

Alternative Names

CD307d antigen; CD307d; Fc receptor homolog 4; Fc receptor-like 4; FcRH4; FCRH4Fc receptor-like protein 4; FCRL4; FcR-like protein 4; hIFGP2; IFGP family protein 2; IFGP2; IGFP2; Immune receptor translocation-associated protein 1; immunoglobulin superfamily Fc receptor, gp42; immunoglobulin superfamily receptor translocation associated 1; IRTA1; IRTA1MGC150523; MGC150522

Molecular Weight

Mass (kDA):
57.224 kDA

Genomic Context


Human

Location:	1q23.1
Sequence:	1; NC_000001.11 (157573747..157598085, complement)

Tissue Specificity

Specifically expressed by memory and monocytoid B-cells which populate spleen and lymph nodes. Preferentially expressed in memory B-cells associated with mucosal tissue (at protein level).

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Malignant Neoplasms
Exhaustion
Hiv Infections
Neoplasms
Infective Disorder
Hepatitis C, Chronic
Multiple Myeloma
Malaria
Lymphoma
Chronic Lymphocytic Leukemia
Cell Transformation, Neoplastic
Hepatitis
Hepatitis C

Autoimmune Diseases
Virus Diseases
Autoimmune Reaction
Leukemia
Chromosomal Translocation
Leukemia, B-cell
Lymphoproliferative Disorders

Interacting Proteins

TFF1
TFF2

Pathways

Leukocyte Differentiation
Cell Activation
Cell Proliferation
Cell Development
Dna Methylation
Glycosylation
Plasma Cell Differentiation
B Cell Proliferation
Localization

Methylation
Cell Differentiation
Isotype Switching
Pathogenesis

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCRL4

References

PMID: 11290337 by Hatzivassiliou G., et al. IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy.

PMID: 11493702 by Davis R.S., et al. Identification of a family of Fc receptor homologs with preferential B cell expression.