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- Table of Contents
FECH Antibodies
AND FECH ELISA kits, FECH Proteins
Many biological assays use antibodies to detect FECH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FECH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FECH antibodies...
Designing a Western blot for FECH? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FECH Western Blot GuideDesigning an IHC experiment for FECH? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the FECH IHC GuideFECH Infographic by Boster Bio
All FECH Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$405
Cat # A05156
100ul
Cat # A05156
100ul
FECH Overview
Facts about Ferrochelatase, mitochondrial.
Ferrochelatase, mitochondrial (FECH)
Catalyzes the ferrous insertion into protoporphyrin IX. .
Gene Information
| Human | |
|---|---|
| Gene Name: | FECH |
| Uniprot: | P22830 |
| Entrez: | 2235 |
Family
| Belongs to: |
|---|
| ferrochelatase family |
Alternative Names
EC 4.99.1.1; EPP; FCE; ferrochelatase (protoporphyria); ferrochelatase; ferrochelatase, mitochondrial; Heme synthase; heme synthetase; Protoheme ferro-lyase; protoporphyria
Molecular Weight
Mass (kDA):
47.862 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q21.31 |
| Sequence: | 18; NC_000018.10 (57544377..57586708, complement) |
Subcellular Localizations
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Diseases
- Erythropoietic Protoporphyria
- Disorders Of Porphyrin Metabolism
- Liver Diseases
- Hepatoerythropoietic Porphyria
- Porphyria, Erythropoietic
- Anemia
- Photosensitivity Disorders
- Liver Failure
- Malignant Neoplasms
- Neoplasms
- Liver Damage
- Hereditary Diseases
Interacting Proteins
- PGRMC1
Pathways
- Excretion
- Localization
- Pathogenesis
- Transport
- Methylation
- Reverse Transcription
- Cell Adhesion
- Cell Development
- Aging
- Immune Response
- Protein Oxidation
- Metaphase
PTMs
- Methylation
- Phosphorylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FECH
bosterbio.com/bosterbio-gene-info-cards/FECH
References
PMID: 2260980 by Nakahashi Y., et al. Molecular cloning and sequence analysis of cDNA encoding human ferrochelatase.
PMID: 7983009 by Tugores A., et al. A single promoter directs both housekeeping and erythroid preferential expression of the human ferrochelatase gene.