FECH Antibodies

AND FECH ELISA kits, FECH Proteins

Many biological assays use antibodies to detect FECH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FECH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FECH antibodies...

We validate the specificity of these antibodies to FECH by testing them on tissues known to express FECH positively and negatively. Browse below to find the FECH antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FECH Infographic by Boster Bio

All FECH Products

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Product

Figures

Specificity

Applications

Price

Anti-Ferrochelatase, mitochondrial FECH Antibody

Western blot analysis of extracts of various cell lines, using FECH antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded human stomach using FECH antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded rat heart using FECH antibody at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A05156
100ul

FECH (NM_000140) Human Recombinant Protein

Coomassie blue staining of purified FECH protein

$1062
Cat # PROTP22830
20 µg

Anti-FECH antibody

IHC analysis of FECH using anti-FECH antibody (A05156-2)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A05156-2
100 μl/vial

FECH Overview

Facts about Ferrochelatase, mitochondrial.

FECH 3D structure. Source: alphafold

Ferrochelatase, mitochondrial (FECH)

Catalyzes the ferrous insertion into protoporphyrin IX. .

Gene Information

Human
Gene Name:	FECH
Uniprot:	P22830
Entrez:	2235

Family

Belongs to:

ferrochelatase family

Alternative Names

EC 4.99.1.1; EPP; FCE; ferrochelatase (protoporphyria); ferrochelatase; ferrochelatase, mitochondrial; Heme synthase; heme synthetase; Protoheme ferro-lyase; protoporphyria

Molecular Weight

Mass (kDA):
47.862 kDA

Genomic Context


Human

Location:	18q21.31
Sequence:	18; NC_000018.10 (57544377..57586708, complement)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Diseases

Erythropoietic Protoporphyria
Disorders Of Porphyrin Metabolism
Liver Diseases
Hepatoerythropoietic Porphyria
Porphyria, Erythropoietic
Anemia
Photosensitivity Disorders
Liver Failure
Malignant Neoplasms
Neoplasms
Liver Damage
Hereditary Diseases

Hypokinesia
Cholestasis
Microcytic Anemia
Erythema
Carcinoma
Porphyrias, Hepatic

Interacting Proteins

PGRMC1

Pathways

Excretion
Localization
Pathogenesis
Transport
Methylation
Reverse Transcription
Cell Adhesion
Cell Development
Aging
Immune Response
Protein Oxidation
Metaphase

Senescence
Drug Resistance
Cell Cycle
Interphase
Nucleocytoplasmic Transport
Photoprotection

PTMs

Methylation
Phosphorylation

Cleavage
Oxidation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FECH

References

PMID: 2260980 by Nakahashi Y., et al. Molecular cloning and sequence analysis of cDNA encoding human ferrochelatase.

PMID: 7983009 by Tugores A., et al. A single promoter directs both housekeeping and erythroid preferential expression of the human ferrochelatase gene.