FKBP4 Antibodies

AND FKBP4 ELISA kits, FKBP4 Proteins

Many biological assays use antibodies to detect FKBP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FKBP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FKBP4 antibodies...

We validate the specificity of these antibodies to FKBP4 by testing them on tissues known to express FKBP4 positively and negatively. Browse below to find the FKBP4 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FKBP4 Infographic by Boster Bio

All FKBP4 Products

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Specificity

Applications

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Anti-FKBP4 Antibody

Western blot analysis of extracts of various cell lines, using FKBP52/FKBP4 antibody at 1:1000 dilution

Immunofluorescence analysis of U2OS cells using FKBP52/FKBP52/FKBP4 antibody

Immunohistochemistry of paraffin-embedded human lung cancer using FKBP52/FKBP52/FKBP4 Rabbit pAb at dilution of 1:100

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$405
Cat # A02165
100ul

Anti-FKBP52 FKBP4 Antibody

Western blot analysis of FKBP52 on 293 (1) and SK-Br-3 (2) cell lysate using anti-FKBP52 antibody at 1/2,000 dilution

ICC staining FKBP52 in 293T cells (green)

Human, Mouse

Flow Cytometry, IHC, ICC, WB

$405
Cat # A02165-1
100ul

Anti-FKBP4 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A02165-2
100ul

FKBP52 (FKBP4) (NM_002014) Human Recombinant Protein

Coomassie blue staining of purified FKBP4 protein

$1062
Cat # PROTQ02790
20 µg

Anti-FKBP52 Rabbit Monoclonal Antibody

Western blot analysis of FKBP52 expression in MCF7 cell lysate

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M02165-2
100 μl/vial

Anti-FKBP52/FKBP4 Antibody Picoband®

Western blot analysis of FKBP52/FKBP4 using anti-FKBP52/FKBP4 antibody (A02165-3)

Human, Mouse, Rat

$370
Cat # A02165-3
100 μg/vial

FKBP52 (FKBP4) (NM_002014) Human Over-expression Lysate

Human

$628
Cat # LS002288
20 µg, 100 µg

FKBP4 Overview

Facts about Peptidyl-prolyl cis-trans isomerase FKBP4.

FKBP4 3D structure. Source: alphafold

Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4)

Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90).

May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.

Gene Information

Human
Gene Name:	FKBP4
Uniprot:	Q02790
Entrez:	2288

Family

Belongs to:

No superfamily

Alternative Names

51 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; EC 5.2.1.8; FK506 binding protein 4, 59kDa; FK506-binding protein 4 (59kD); FK506-binding protein 4; FKBP4; FKBP-4; FKBP51; FKBP52; FKBP-52; FKBP52T-cell FK506-binding protein, 59kD; FKBP59; FKBP5952 kDa FK506-binding protein; HBI; HSP binding immunophilin; Hsp56; HSP-binding immunophilin; Immunophilin FKBP52; p52; p59; peptidyl-prolyl cis-trans isomerase FKBP4; peptidylprolyl cis-trans isomerase; PPIase FKBP4; PPIase; rotamase

Molecular Weight

Mass (kDA):
51.805 kDA

Genomic Context


Human

Location:	12p13.33
Sequence:	12; NC_000012.12 (2794970..2805423)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Cytoplasm, cytosol. Mitochondrion. Nucleus. Cytoplasm, cytoskeleton. Cell projection, axon. Shuttles from mitochondria to nucleus; co-localizes in mitochondria with the glucocorticoid receptor (PubMed:21730050). Colocalized with MAPT/TAU in the distal part of the primary cortical neurons (By similarity).

Diseases

Malignant Neoplasms
Neoplasms
Major Depressive Disorder
Depressive Disorder
Malignant Neoplasm Of Breast
Infertility
Immunologic Deficiency Syndromes
Mammary Neoplasms
Mental Disorders
Prostatic Neoplasms
Inflammation
Carcinogenesis

Malignant Neoplasm Of Prostate
Hypertensive Disease
Hiv Infections
Ocular Hypertension
Cholangiocarcinoma
Seminoma
Neoplasms, Experimental

Interacting Proteins

AGO2
AR
CDC37
GLMN
HSP90AA1

HSP90AB1
HSPB1
S100a1
S100A2
S100A6

Pathways

Methylation
Pathogenesis
Cell Death
Protein Folding
Response To Stress
Fatty Acid Elongation
Immune Response
Dna Methylation
Proteolysis
Fatty Acid Beta-oxidation
Ovulation

Localization
Cell Maturation
Rna Splicing
Drug Resistance
Decidualization

PTMs

Methylation

Oxidation

Phosphorylation

Research Areas

Membrane Trafficking and Chaperones
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FKBP4

References

PMID: 1279700 by Peattie D.A., et al. Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes.

PMID: 1376003 by Tai P.-K.K., et al. Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex.