Forkhead box protein I1 Antibodies

AND FOXI1 ELISA kits, Forkhead box protein I1 Proteins

Many biological assays use antibodies to detect Forkhead box protein I1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Forkhead box protein I1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Forkhead box protein I1 antibodies...

We validate the specificity of these antibodies to Forkhead box protein I1 by testing them on tissues known to express FOXI1 positively and negatively. Browse below to find the FOXI1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FOXI1 Infographic by Boster Bio

All FOXI1 Products

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Anti-Forkhead box protein I1 FOXI1 Antibody

5 Q&As

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using FOXI1 Antibody

Human, Mouse

ELISA, IF, IHC, ICC, WB

$335
Cat # A07512-1
100ul

Anti-Forkhead box protein I1 FOXI1 Antibody Picoband®

Western blot analysis of FOXI1 using anti-FOXI1 antibody (A07512-3)

IF analysis of FOXI1 using anti-FOXI1 antibody (A07512-3)

Flow Cytometry analysis of A549 cells using anti-FOXI1 antibody (A07512-3)

Human, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A07512-3
100 μg/vial

Anti-FOXI1 Mouse Monoclonal Antibody [Clone ID: OTI1D4]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOXI1 (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-FOXI1 mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FOXI1 mouse monoclonal antibody

Human, Mouse

Flow Cytometry, IF, IHC, WB

$523
Cat # M07512
100 µl

FOXI1 (NM_012188) Human Over-expression Lysate

FOXI1 Human Over-expression Lysates NM_012188

Human

$628
Cat # LS002299
20 µg, 100 µg

FOXI1 Overview

Facts about Forkhead box protein I1.

FOXI1 3D structure. Source: alphafold

Forkhead box protein I1 (FOXI1)

Transcriptional activator required for the progression of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear.

Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity). .

Gene Information

Human
Gene Name:	FOXI1
Uniprot:	Q12951
Entrez:	2299

Family

Belongs to:

No superfamily

Alternative Names

FKHL10HFH3; forkhead box I1; forkhead box protein I1; forkhead-like 10; forkhead-related activator 6; Forkhead-related protein FKHL10; Forkhead-related transcription factor 6; FREAC-6; FREAC6FKH10; Hepatocyte nuclear factor 3 forkhead homolog 3; HFH-3; HNF-3/fork-head homolog 3; HNF-3/fork-head homolog-3; MGC34197

Molecular Weight

Mass (kDA):
40.973 kDA

Genomic Context


Human

Location:	5q35.1
Sequence:	5; NC_000005.10 (170105897..170109734)

Tissue Specificity

Expressed in kidney.

Subcellular Localizations

Nucleus.

Diseases

Pendred's Syndrome
Sensorineural Hearing Loss (disorder)
Acidosis
Renal Tubular Acidosis
Complete Hearing Loss
Crest Syndrome
Nodular Goiter
Renal Tubular Acidosis, Type I
Nervousness
Dysplasia
Neoplasms
Trematode Infections
Liver Carcinoma

Congenital Ear Anomaly Nos (disorder)
Pathological Dilatation
Hypertensive Disease
Essential Hypertension
Disease Of Adrenal Medulla
Jaw Abnormalities
Respirovirus Infections

Interacting Proteins

VPS37C

Pathways

Gastrulation
Cell Differentiation
Ear Development
Transport
Neurogenesis
Inner Ear Development
Epithelial Cell Differentiation
Cell Death
Cell Fate Determination
Otic Placode Formation
Ion Transport
Regeneration
Pathogenesis

Cell Migration
Neural Crest Cell Migration
Developmental Process
Fertilization
Lung Development
Hypersensitivity
Sweat Gland Development

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FOXI1

References

PMID: 9153225 by Overdier D.G., et al. The winged helix transcriptional activator HFH-3 is expressed in the distal tubules of embryonic and adult mouse kidney.

PMID: 7957066 by Pierrou S., et al. Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.