Fascin-2 Antibodies

AND FSCN2 ELISA kits, Fascin-2 Proteins

Many biological assays use antibodies to detect Fascin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fascin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fascin-2 antibodies...

We validate the specificity of these antibodies to Fascin-2 by testing them on tissues known to express FSCN2 positively and negatively. Browse below to find the FSCN2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FSCN2 Infographic by Boster Bio

All FSCN2 Products

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Anti-Fascin 2/FSCN2 Antibody Picoband®

1 Q&As

Western blot analysis of FSCN2 using anti-FSCN2 antibody (A07840-2)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A07840-2
100 μg/vial

Fascin 2 (FSCN2) (NM_012418) Human Over-expression Lysate

Fascin 2 (FSCN2) Human Over-expression Lysates NM_001077182

Human

$960
Cat # LS025794
20 µg, 100 µg

FSCN2 Overview

Facts about Fascin-2.

FSCN2 3D structure. Source: alphafold

Fascin-2 (FSCN2)

Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disc morphogenesis.

Gene Information

Human
Gene Name:	FSCN2
Uniprot:	O14926
Entrez:	25794

Family

Belongs to:

fascin family

Alternative Names

fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotuspurpuratus); fascin-2; Retinal fascin; retinal); RFSNRP30fascin (Strongylocentrotus purpuratus) homolog 2 (actin-bundling protein

Molecular Weight

Mass (kDA):
55.057 kDA

Genomic Context


Human

Location:	17q25.3
Sequence:	17; NC_000017.11 (81513019..81537130)

Tissue Specificity

Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection, stereocilium.

Diseases

Retinitis Pigmentosa
Retinal Degeneration
Age Related Macular Degeneration
Retinal Diseases
Hereditary Diseases
Dystrophy
Amaurosis
Fracture Of First Cervical Vertebra
Macule
Genetic Diseases, X-linked
Atrophy

Atrophic Retina
Blind Vision
Haploinsufficiency
Leber Congenital Amaurosis
Dog Diseases

Pathways

Pathogenesis
Methylation
Reverse Transcription

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FSCN2

References

PMID: 10234509 by Bardien-Kruger S., et al. Refinement of the RP17 locus for autosomal dominant retinitis pigmentosa, construction of a YAC contig and investigation of the candidate gene retinal fascin.

PMID: 10783262 by Tubb B.E., et al. Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes.