FREM1 Antibodies

AND FREM1 ELISA kits, FREM1 Proteins

Many biological assays use antibodies to detect FREM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FREM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FREM1 antibodies...

We validate the specificity of these antibodies to FREM1 by testing them on tissues known to express FREM1 positively and negatively. Browse below to find the FREM1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FREM1 Infographic by Boster Bio

All FREM1 Products

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Product

Figures

Specificity

Applications

Price

Anti-FREM1 Antibody

Western blot analysis of FREM1 in K562 cell lysate with FREM1 antibody at (A) 0

Immunocytochemistry of FREM1 in K562 cells with FREM1 antibody at 20 μg/mL

Immunofluorescence of FREM1 in K562 cells with FREM1 antibody at 20 μg/mL

Human, Mouse

ELISA, IF, ICC, WB

$481
Cat # A09605
0.1 mg

Anti-FREM1 Antibody

Western blot analysis of extracts of various cell lines, using FREM1 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A09605-1
100ul

FREM1 (NM_144966) Human Recombinant Protein

Coomassie blue staining of purified FREM1 protein

$1249
Cat # PROTQ5H8C1
20 µg

FREM1 (NM_144966) Human Over-expression Lysate

Human

$960
Cat # LS158326
20 µg, 100 µg

FREM1 Overview

Facts about FRAS1-related extracellular matrix protein 1.

FREM1 3D structure. Source: alphafold

FRAS1-related extracellular matrix protein 1 (FREM1)

Extracellular matrix protein which plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development. .

Gene Information

Human
Gene Name:	FREM1
Uniprot:	Q5H8C1
Entrez:	158326

Family

Belongs to:

FRAS1 family

Alternative Names

BNAR; C9orf143chromosome 9 open reading frame 154; C9orf145C9orf154extracellular matrix protein QBRICK; C9orf154; DKFZp686M16108; FLJ25461; FRAS1 related extracellular matrix 1; FRAS1-related extracellular matrix protein 1; FREM1; Protein QBRICK; QBRICK; TILRR

Molecular Weight

Mass (kDA):
244.154 kDA

Genomic Context


Human

Location:	9p22.3
Sequence:	9; NC_000009.12 (14733486..14911653, complement)

Subcellular Localizations

Secreted, extracellular space, extracellular matrix, basement membrane. Localizes at the basement membrane zone of embryonic epidermis and hair follicles.

Diseases

Cryptophthalmos Syndrome
Bulla
Cryptophthalmos
Syndactyly
Congenital Absence
Congenital Absence Of Kidney
Tissue Adhesions
Congenital Abnormality
Multisystem Disorder
Hereditary Diseases
Congenital Cleft Nose
Congenital Ocular Coloboma (disorder)

Epidermolysis Bullosa
Orbital Separation Excessive
Epidermolysis Bullosa Dystrophica
Anus, Imperforate
Developmental Delay (disorder)
Fused Eyelid
Strabismus

Interacting Proteins

FREM2

Pathways

Localization
Cell Adhesion
Fin Development
Basement Membrane Assembly
Fin Morphogenesis
Translation
Membrane Assembly

Pathogenesis
Kidney Development

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FREM1

References

PMID: 15878328 by Kiyozumi D., et al. Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

PMID: 19732862 by Alazami A.M., et al. FREM1 mutations cause bifid nose, renal agenesis, and anorectal malformations syndrome.