Grancalcin Antibodies

AND GCA ELISA kits, Grancalcin Proteins

Many biological assays use antibodies to detect Grancalcin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Grancalcin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Grancalcin antibodies...

We validate the specificity of these antibodies to Grancalcin by testing them on tissues known to express GCA positively and negatively. Browse below to find the GCA antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GCA Infographic by Boster Bio

All GCA Products

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Anti-Grancalcin/GCA Antibody Picoband®

3 Q&As

Western blot analysis of Grancalcin/GCA using anti-Grancalcin/GCA antibody (A01237)

IHC analysis of Grancalcin/GCA using anti-Grancalcin/GCA antibody (A01237)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01237
100 μg/vial

Grancalcin (GCA) (NM_012198) Human Recombinant Protein

Coomassie blue staining of purified GCA protein

$1249
Cat # PROTP28676
20 µg

Grancalcin (GCA) (NM_012198) Human Over-expression Lysate

Human

$628
Cat # LS025801
20 µg, 100 µg

GCA Overview

Facts about Grancalcin.

GCA 3D structure. Source: alphafold

Grancalcin (GCA)

Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.

Gene Information

Human
Gene Name:	GCA
Uniprot:	P28676
Entrez:	25801

Family

Belongs to:

No superfamily

Alternative Names

EF-hand calcium-binding protein; grancalcin, EF-hand calcium binding protein; grancalcin, penta-EF-hand protein

Molecular Weight

Mass (kDA):
24.01 kDA

Genomic Context


Human

Location:	2q24.2
Sequence:	2; NC_000002.12 (162318763..162377225)

Tissue Specificity

Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.

Subcellular Localizations

Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side. Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels.

Diseases

Giant Cell Arteritis
Arteritis
Polymyalgia Rheumatica
Vasculitis
Malignant Neoplasms
Inflammation
Neoplasms
Carcinoma
Headache
Stomach Neoplasms
Adenocarcinoma
Blind Vision

Temporal Arteritis
Claudication (finding)
Ischemia
Visual Impairment
Malignant Squamous Cell Neoplasm
Esophageal Neoplasms
Pain

Interacting Proteins

MAGEA8

Pathways

Pathogenesis
Translation
Mating
Transport
Inflammatory Response
Methylation
Localization
Excretion
Immune Response
Conjugation
Angiogenesis
Secretion
Cell Adhesion

Cell Proliferation
Cell Growth
Cell Migration
Fermentation
Trna Aminoacylation
Oncogenesis
Response To Stress

PTMs

Methylation
Phosphorylation
Cleavage
Nitration
Biotinylation

Oxidation
Reduction
Deamination
Acetylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCA

References

PMID: 1737748 by Boyhan A., et al. Molecular cloning and characterization of grancalcin, a novel EF-hand calcium-binding protein abundant in neutrophils and monocytes.

PMID: 1530588 by Teahan C.G., et al. Isolation and characterization of grancalcin, a novel 28 kDa EF-hand calcium-binding protein from human neutrophils.