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- Table of Contents
Grancalcin Antibodies
AND GCA ELISA kits, Grancalcin Proteins
Many biological assays use antibodies to detect Grancalcin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Grancalcin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Grancalcin antibodies...
Designing a Western blot for Grancalcin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GCA Western Blot GuideGCA Infographic by Boster Bio
All GCA Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01237
100 μg/vial
Cat # A01237
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A07144-1
100 μg/vial
Cat # A07144-1
100 μg/vial
GCA Overview
Facts about Grancalcin.
Grancalcin (GCA)
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | GCA |
| Uniprot: | P28676 |
| Entrez: | 25801 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
EF-hand calcium-binding protein; grancalcin, EF-hand calcium binding protein; grancalcin, penta-EF-hand protein
Molecular Weight
Mass (kDA):
24.01 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q24.2 |
| Sequence: | 2; NC_000002.12 (162318763..162377225) |
Tissue Specificity
Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.
Subcellular Localizations
Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side. Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels.
Diseases
- Giant Cell Arteritis
- Arteritis
- Polymyalgia Rheumatica
- Vasculitis
- Malignant Neoplasms
- Inflammation
- Neoplasms
- Carcinoma
- Headache
- Stomach Neoplasms
- Adenocarcinoma
- Blind Vision
Interacting Proteins
- MAGEA8
Pathways
- Pathogenesis
- Translation
- Mating
- Transport
- Inflammatory Response
- Methylation
- Localization
- Excretion
- Immune Response
- Conjugation
- Angiogenesis
- Secretion
- Cell Adhesion
PTMs
- Methylation
- Phosphorylation
- Cleavage
- Nitration
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCA
bosterbio.com/bosterbio-gene-info-cards/GCA
References
PMID: 1737748 by Boyhan A., et al. Molecular cloning and characterization of grancalcin, a novel EF-hand calcium-binding protein abundant in neutrophils and monocytes.
PMID: 1530588 by Teahan C.G., et al. Isolation and characterization of grancalcin, a novel 28 kDa EF-hand calcium-binding protein from human neutrophils.