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- Table of Contents
Gcsam Antibodies
AND Gcsam ELISA kits, Gcsam Proteins
Many biological assays use antibodies to detect Gcsam, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gcsam in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gcsam antibodies...
Designing an IHC experiment for Gcsam? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the GCSAM IHC GuideGcsam Infographic by Boster Bio
All Gcsam Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC
$146
Cat # M12995-1
20μL, 40μL, 100μL, 200μL
Cat # M12995-1
20μL, 40μL, 100μL, 200μL
Gcsam Overview
Facts about Germinal center-associated signaling and motility protein.
Germinal center-associated signaling and motility protein (Gcsam)
Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6.
Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation leads to inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Gcsam |
| Uniprot: | Q6RFH4 |
| Entrez: | 14525 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
GAL; GCAT2; germinal center B-cell-expressed transcript 2 protein; germinal center expressed transcript 2; Germinal center-associated lymphoma protein; HGAL; MGC40441
Molecular Weight
Mass (kDA):
20.988 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 16|16 B5 |
| Sequence: | 16; |
Tissue Specificity
Highly expressed in normal germinal center (GC) B-cells. Expressed in spleen and, to a lesser extent, bone marrow.
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Gcsam
bosterbio.com/bosterbio-gene-info-cards/Gcsam
References
PMID: 7981148 by Christoph T., et al. M17: a novel gene expressed in germinal centers.
PMID: 23299888 by Romero-Camarero I., et al. Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation.