GINS4 Antibodies

AND GINS4 ELISA kits, GINS4 Proteins

Many biological assays use antibodies to detect GINS4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GINS4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GINS4 antibodies...

We validate the specificity of these antibodies to GINS4 by testing them on tissues known to express GINS4 positively and negatively. Browse below to find the GINS4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for GINS4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the GINS4 IHC Guide

GINS4 Infographic by Boster Bio

All GINS4 Products

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Specificity

Applications

Price

Anti-SLD5/GINS4 Antibody Picoband®

Western blot analysis of SLD5/GINS4 using anti-SLD5/GINS4 antibody (A10548-1)

IHC analysis of SLD5/GINS4 using anti-SLD5/GINS4 antibody (A10548-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A10548-1
100 μg/vial

SLD5 (GINS4) (NM_032336) Human Over-expression Lysate

Human

$628
Cat # LS084296
20 µg, 100 µg

SLD5 (GINS4) (NM_032336) Human Recombinant Protein

Coomassie blue staining of purified GINS4 protein

$1249
Cat # PROTQ9BRT9
20 µg

GINS4 Overview

Facts about DNA replication complex GINS protein SLD5.

GINS4 3D structure. Source: alphafold

DNA replication complex GINS protein SLD5 (GINS4)

The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly.

GINS complex seems to bind preferentially to single-stranded DNA. .

Gene Information

Human
Gene Name:	GINS4
Uniprot:	Q9BRT9
Entrez:	84296

Family

Belongs to:

GINS4/SLD5 family

Alternative Names

DNA replication complex GINS protein SLD5; GINS complex subunit 4 (Sld5 homolog); GINS complex subunit 4; SLD5 homolog; SLD5MGC14799

Molecular Weight

Mass (kDA):
26.047 kDA

Genomic Context


Human

Location:	8p11.21
Sequence:	8; NC_000008.11 (41529205..41545030)

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Malignant Neoplasms
Cell Invasion
Neoplasm Metastasis
Prostatic Neoplasms
Neoplasms
Primary Neoplasm
Melanoma
Malignant Neoplasm Of Breast
Mammary Neoplasms

Malignant Paraganglionic Neoplasm
Tissue Adhesions
Neoplasm Invasiveness

Interacting Proteins

GINS2
MCMBP

Pathways

Dna Replication
Translation
Melanocyte Differentiation
Cell Cycle

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GINS4

References

PMID: 17170760 by De Falco M., et al. The human GINS complex binds to and specifically stimulates human DNA polymerase alpha-primase.

PMID: 17611626 by Ryu B., et al. Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression.