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- Table of Contents
GJB1 Antibodies
AND GJB1 ELISA kits, GJB1 Proteins
Many biological assays use antibodies to detect GJB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GJB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GJB1 antibodies...
Designing a Western blot for GJB1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GJB1 Western Blot GuideGJB1 Infographic by Boster Bio
All GJB1 Products
Product
Figures
Specificity
Applications
Price
Anti-Connexin 32/GJB1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1367
100 μg/vial
Cat # PA1367
100 μg/vial
Human
ELISA, Flow Cytometry, WB
$370
Cat # A01050-1
100 µg/vial
Cat # A01050-1
100 µg/vial
GJB1 Overview
Facts about Gap junction beta-1 protein.
Gap junction beta-1 protein (GJB1)
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .
Gene Information
| Human | |
|---|---|
| Gene Name: | GJB1 |
| Uniprot: | P08034 |
| Entrez: | 2705 |
Family
| Belongs to: |
|---|
| connexin family |
Alternative Names
CMTX; CMTX1; Connexin 32; Connexin-32; CX32; CX32beta 1, 32kD (connexin 32, Charcot-Marie-Toothneuropathy, X-linked); gap junction beta-1 protein; gap junction protein, beta 1, 32kDa (connexin 32); gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Toothneuropathy, X-linked); gap junction protein, beta 1, 32kDa; GJB1
Molecular Weight
Mass (kDA):
32.025 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq13.1 |
| Sequence: | X; NC_000023.11 (71215212..71225516) |
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Diseases
- Charcot-marie-tooth Disease
- Peripheral Neuropathy
- Hereditary Motor And Sensory Neuropathies
- Genetic Diseases, X-linked
- Nervousness
- Sensory Neuropathy
- Inherited Neuropathy
- Weakness
- X-linked Hereditary Motor And Sensory Neuropathy
- Atrophy
- Polyneuropathy
- Complete Hearing Loss
Pathways
- Localization
- Pathogenesis
- Myelination
- Transport
- Muscle Atrophy
- Translation
- Mitochondrial Fusion
- Myelin Maintenance
- Dna Methylation
- Methylation
- Cell Adhesion
- Dna Hypermethylation
- Dna Hypomethylation
PTMs
- Methylation
- Sumoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GJB1
bosterbio.com/bosterbio-gene-info-cards/GJB1
References
PMID: 2875078 by Kumar N.M., et al. Cloning and characterization of human and rat liver cDNAs coding for a gap junction protein.
PMID: 2460334 by Milks L.C., et al. Topology of the 32-kd liver gap junction protein determined by site- directed antibody localizations.