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1 Q&As
Facts about Guanine nucleotide-binding protein G(q) subunit alpha.
Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). .
Human | |
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Gene Name: | GNAQ |
Uniprot: | P50148 |
Entrez: | 2776 |
Belongs to: |
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G-alpha family |
GAQG-ALPHA-q; guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding protein alpha-q; guanine nucleotide-binding protein G(q) subunit alpha
Mass (kDA):
42.142 kDA
Human | |
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Location: | 9q21.2 |
Sequence: | 9; NC_000009.12 (77716097..78031811, complement) |
Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level).
Nucleus. Membrane. Nucleus membrane. Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.
For those of you who are unfamiliar about the GNAQ Marker here are the most effective uses of this biomarker. Boster Bio provides researchers with research primary antibodies as well as secondary antibodies for a range of applications such as ELISA kits. These ELISA kits are specifically designed to be used in research and are available to researchers worldwide. Boster Bio has three products for your research needs which include Super Vision Detection Kits (SuperViD) and PICOKINE(tm) ELISA kits.
Boster Bio's primary and secondary antibody products include antibodies for neurodegenerative diseases, cancer, neuroscience and inflammation. Boster Biologicals offers more than 16,000 antibodies that cover a broad range of applications. The company's top-quality antibodies, ELISA kits and reagents have been tested for quality and quality control. To ensure top quality and efficiency, the company produces antibodies and ELISA kit in-house. These reagents can be purchased through its tebu-bio brand.
B cells that have been primed with the antigen are multiplied 10 to 100-fold and produce antibodies with increased affinity. The secondary antibody response continues to increase the affinity of antibodies. This response is characterised by low levels of IgM antibodies, and large quantities of IgG and IgA antibodies are generated. As a result memory B cells are identified and switched from producing IgM antibodies to more mature isotypes.
Additionally, secondary antibodies are available to target CH2 or CH3 domains of immunoglobulins. These antibodies can be used to research new therapeutic antibody fragments. The company also offers a wide array of immunoglobulins for various research needs. They can be used to target the CH2 or CH3 domains of immunoglobulins as well as to investigate their interactions with Fc fragments.
The synthesis of secondary antibodies starts with a polyclonal rabbit polyclonal. The secondary antibody then detects primary antibody. It is then detected with the aid of a secondary antibody labeled with a reporter molecule such as HRP or FITC. Sometimes the secondary antibody binds to the antibody domain of an recombinant protein. This engineered protein may be used to facilitate the ease of expression.
Boster Bio manufactures quality reagents and kits to meet your specific needs. Their range of products includes well-known assay kits and buffers, lysates and controls, and solutions. The company is a specialist in high-specificity and high-sensitivity antibody and has spent the past two decades perfecting techniques and technology that produce the most accurate results. They have over 29,000 citations for their antibody that have been validated to be used in a variety of applications, including IHC, WB, ELISA, Flow Cytometry, and ELISA.
Boster Bio's PICOKINE (r) Kit for ELISA testing the GNAQ markers has been thoroughly tested against more than 250 tissues and proteins. Picokine(tm), a proprietary technology, is used to greatly enhance binding efficiency and reduce non-specific binding. They come with enough reagents for you to perform 96 tests.
The PICOKINE(tm) RNAi ELISA kits detect GNAQ protein expression levels and determine the relative abundance of GNAQ protein in microbial cells. Boster Bio's PICOKINE(tm) ELISA kits for the GNAQ marker are available through Sanbio which offers GNAQ RNAi, PCR and other biomarker tests. The website of the company has hyperlinks to the ELISA kits as well as custom services and BeNeLux delivery.
Picoband is an ELISA platform that can increase the an individual's sensitivity by the amount of 10. The ELISA can be validated for a range of samples. Images are available on request. Supervision is the secondary antibody it employs, can cut down on up to 30 minutes of IHC. PICOBAND is powered by research into the design of immunogens and is supported in part by Sanbio which is a BeNeLux distributor.
To ensure the best performance, the antibodies are tested on multiple platforms, including WB and IHC assays. Boster's antibodies have been tested in a quantitative manner against recombinant proteins, as well as panels of more than 250 tissues. These antibodies are highly specific, highly affinity. Boster Bio's PICOBAND(tm) ELISA kits for the GNAQ marker are based on a solid validation program that rewards the first reviewers with product credits. These benefits extend to scientists across the globe.
PMID: 8825633 by Dong Q., et al. Molecular cloning of human G alpha q cDNA and chromosomal localization of the G alpha q gene (GNAQ) and a processed pseudogene.
PMID: 8664309 by Chen B., et al. Human G(alpha q): cDNA and tissue distribution.