This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
GNAQ Antibodies
AND GNAQ ELISA kits, GNAQ Proteins
Many biological assays use antibodies to detect GNAQ, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNAQ in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNAQ antibodies...
Designing a Western blot for GNAQ? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GNAQ Western Blot GuideGNAQ Infographic by Boster Bio
All GNAQ Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9707
100 μg/vial
Cat # PB9707
100 μg/vial
Human, Monkey, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M00898
100 μg/vial
Cat # M00898
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00898-1
100 μl/vial
Cat # M00898-1
100 μl/vial
GNAQ Overview
Facts about Guanine nucleotide-binding protein G(q) subunit alpha.
Guanine nucleotide-binding protein G(q) subunit alpha (GNAQ)
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell choice and survival and is required to prevent B-cell-dependent autoimmunity.
Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | GNAQ |
| Uniprot: | P50148 |
| Entrez: | 2776 |
Family
| Belongs to: |
|---|
| G-alpha family |
Alternative Names
GAQG-ALPHA-q; guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding protein alpha-q; guanine nucleotide-binding protein G(q) subunit alpha
Molecular Weight
Mass (kDA):
42.142 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q21.2 |
| Sequence: | 9; NC_000009.12 (77716097..78031811, complement) |
Tissue Specificity
Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level).
Subcellular Localizations
Nucleus. Membrane. Nucleus membrane. Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.
Diseases
- Melanoma
- Neoplasms
- Uveal Melanoma
- Malignant Neoplasms
- Uveal Neoplasms
- Melanocytic Nevus
- Neoplasm Metastasis
- Malignant Paraganglionic Neoplasm
- Nevus, Blue
- Skin Neoplasms
- Cutaneous Melanoma
- Metastatic Melanoma
Interacting Proteins
- ARRB1
- IQSEC1
- KISS1R
- RARA
- Trpm8
Pathways
- Pathogenesis
- Cell Cycle
- Localization
- Oncogenesis
- Enucleation
- Cell Proliferation
- Secretion
- Cell Adhesion
- Peripheral B Cell Tolerance Induction
- Leukocyte Proliferation
- Proteolysis
- Neurogenesis
- Eating Behavior
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNAQ
bosterbio.com/bosterbio-gene-info-cards/GNAQ
References
PMID: 8825633 by Dong Q., et al. Molecular cloning of human G alpha q cDNA and chromosomal localization of the G alpha q gene (GNAQ) and a processed pseudogene.
PMID: 8664309 by Chen B., et al. Human G(alpha q): cDNA and tissue distribution.