Golgin subfamily A member 2 (GOLGA2)

Peripheral membrane component of this cis-Golgi pile that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane (Probable) (PubMed:16489344). Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane (By similarity).

Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Golgi disassembly: phosphorylation at Ser-37 by CDK1 at the beginning of mitosis inhibits the interaction with p115/USO1, preventing tethering of COPI vesicles and thus inhibiting transport through the Golgi apparatus during mitosis (By similarity).