GPER1 Antibodies

AND GPER1 ELISA kits, GPER1 Proteins

Many biological assays use antibodies to detect GPER1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPER1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPER1 antibodies...

We validate the specificity of these antibodies to GPER1 by testing them on tissues known to express GPER1 positively and negatively. Browse below to find the GPER1 antibody that suites your experiment. We have 15 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for GPER1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the GPER1 Western Blot Guide

GPER1 Infographic by Boster Bio

All GPER1 Products

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Specificity

Applications

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Anti-G-protein coupled receptor 30/GPER1 Antibody Picoband®

Anti-G-protein coupled receptor 30 antibody, PA2235, Western blottingLane 1: COLO320 Cell LysateLane 2: MCF-7 Cell LysateLane 3: COS7 Cell Lysate

Human, Monkey

$370
Cat # PA2235
100 μg/vial

G protein coupled receptor 30 (GPER1) (NM_001505) Human Over-expression Lysate

G protein coupled receptor 30 (GPER1) Human Over-expression Lysates NM_001039966

Human

$628
Cat # LS002852
20 µg, 100 µg

EGFR (Phospho-Ser1071) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HepG2 cells treated with serum 20% 15

Human, Mouse, Rat

ELISA

$540
Cat # EKC2547
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Ser1026) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HeLa cells treated with TSA 400nM 24H

Human, Mouse, Rat

ELISA

$540
Cat # EKC2546
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Ser695) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2545
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Tyr869) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from A431 cells treated with EGF 40 muM 10

Human, Mouse, Rat

ELISA

$540
Cat # EKC2393
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Tyr1172) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2391
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Tyr1110) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HepG2 cells

Human, Mouse, Rat

ELISA

$540
Cat # EKC2390
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Tyr1092) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HuvEc cells treated with EGF

Human, Mouse, Rat

ELISA

$540
Cat # EKC2389
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Ser1070) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from SK-OV3 cells treated with EGF

Human, Mouse, Rat

ELISA

$540
Cat # EKC2388
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Tyr1069) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from COS7 cells treated with EGF 200ng/ml 30

Human, Mouse, Rat

ELISA

$540
Cat # EKC2251
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Tyr1016) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HuvEc cells treated with Serum 20% 30

Human, Mouse, Rat

ELISA

$540
Cat # EKC2065
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Thr693) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from A431 cells

Human, Mouse, Rat

ELISA

$540
Cat # EKC1940
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Thr678) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC1939
1 kit, containing two 96-well plates and all necessary reagents

EGFR (Phospho-Tyr1197) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2392
1 kit, containing two 96-well plates and all necessary reagents

GPER1 Overview

Facts about G-protein coupled estrogen receptor 1.

GPER1 3D structure. Source: alphafold

G-protein coupled estrogen receptor 1 (GPER1)

G-protein coupled estrogen receptor that binds to 17- beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), triggering downstream signaling pathways like PI3K/Akt and ERK/MAPK.

Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a RAMP3-dependent method.

Gene Information

Human
Gene Name:	GPER1
Uniprot:	Q99527
Entrez:	2852

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

CEPR; CEPRG-protein coupled receptor 30; Chemoattractant receptor-like 2; chemokine receptor-like 2; CMKRL2; CMKRL2MGC99678; constitutively expressed peptide-like receptor; DRY12; DRY12IL8-related receptor DRY12; FEG-1; FEG-1mER; Flow-induced endothelial G-protein coupled receptor 1; G protein-coupled estrogen receptor 1; G protein-coupled receptor 30; GPCR-BR; GPER; GPR30; GPR30GPCR-Br; G-protein coupled estrogen receptor 1; heptahelix receptor; LERGU; LERGU2; leucine rich protein in GPR30 3'UTR; LyGPR; Lymphocyte-derived G-protein coupled receptor; Membrane estrogen receptor

Molecular Weight

Mass (kDA):
42.248 kDA

Genomic Context


Human

Location:	7p22.3
Sequence:	7; NC_000007.14 (1086807..1093815)

Tissue Specificity

Expressed in placenta, endothelial and epithelial cells, non laboring and laboring term myometrium, fibroblasts and cancer-associated fibroblasts (CAF), prostate cancer cells and invasive adenocarcinoma (at protein level). Ubiquitously expressed, but is most abundant in placenta. In brain regions, expressed as a 2.8 kb transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen.

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Early endosome. Recycling endosome. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, dendritic spine membrane; Multi-pass membrane protein. Cell projection, axon. Cell junction, synapse, postsynaptic density. Mitocho

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Endometrial Polyp
Carcinoma
Endometrial Carcinoma
Endometrial Neoplasms
Cardiovascular Diseases
Diabetes Mellitus
Ovarian Neoplasm
Cell Invasion
Hyperplasia

Neoplasm Metastasis
Nervousness
Malignant Paraganglionic Neoplasm
Obesity
Inflammation
Carcinogenesis
Seminoma

Pathways

Cell Proliferation
Localization
Secretion
Cell Growth
Insulin Secretion
Cell Cycle
Menopause
Oocyte Maturation
Angiogenesis
Cell Migration
Spermatogenesis
Pathogenesis
Aging

Vasoconstriction
Drug Resistance
Mammary Gland Development
Cell Motility
Lipid Homeostasis
Histone Acetylation
Receptor Transactivation

PTMs

Phosphorylation
Acetylation
Nitrosylation

Ribosylation
Ubiquitination
Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPER1

References

PMID: 8920907 by Owman C.S.O., et al. Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues.

PMID: 9070864 by Feng Y., et al. Cloning of a novel member of the G protein-coupled receptor family related to peptide receptors.