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- Table of Contents
GRM5 Antibodies
AND GRM5 ELISA kits, GRM5 Proteins
Many biological assays use antibodies to detect GRM5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRM5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRM5 antibodies...
Designing a Western blot for GRM5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GRM5 Western Blot GuideGRM5 Infographic by Boster Bio
All GRM5 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01342-1
100 μg/vial
Cat # A01342-1
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A01340-4
100 μg/vial
Cat # A01340-4
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A01348-2
100 μg/vial
Cat # A01348-2
100 μg/vial
Human, Mouse, Rat
ELISA, WB
$370
Cat # A01338-1
100 μg/vial
Cat # A01338-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01345-2
100 μg/vial
Cat # A01345-2
100 μg/vial
Human, Rat
ELISA, WB
$370
Cat # A01338-3
100 µg/vial
Cat # A01338-3
100 µg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01338
100 μl
Cat # M01338
100 μl
Human
$960
Cat # LS002915
20 µg, 100 µg
Cat # LS002915
20 µg, 100 µg
GRM5 Overview
Facts about Metabotropic glutamate receptor 5.
Metabotropic glutamate receptor 5 (GRM5)
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.
Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an essential role in the regulation of synaptic plasticity and the modulation of the neural network activity.
Gene Information
| Human | |
|---|---|
| Gene Name: | GRM5 |
| Uniprot: | P41594 |
| Entrez: | 2915 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 3 family |
Alternative Names
glutamate receptor, metabotropic 5; GPRC1EMGLUR5metabotropic glutamate receptor 5; mGlu5; mGluR5
Molecular Weight
Mass (kDA):
132.469 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q14.2-q14.3 |
| Sequence: | 11; NC_000011.10 (88504576..89065963, complement) |
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Schizophrenia
- Malnutrition
- Attention Deficit Hyperactivity Disorder
- Psychotic Disorders
- Neoplasm Metastasis
- Melanoma
- Ear Neoplasms
- Melanoma, Experimental
- Restless Legs Syndrome
- Autistic Disorder
- Albinism, Oculocutaneous
- Neoplasms
Interacting Proteins
- NECAB2
Pathways
- Chemotaxis
- System Development
- Nervous System Development
- Cell Differentiation
- Synaptic Transmission
- Neurogenesis
- Cell Growth
PTMs
Research Areas
- Neuronal Cell Markers
- Neuroscience
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRM5
bosterbio.com/bosterbio-gene-info-cards/GRM5
References
PMID: 7908515 by Minakami R., et al. Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5.
PMID: 7688218 by Minakami R., et al. A variant of metabotropic glutamate receptor subtype 5: an evolutionally conserved insertion with no termination codon.