Histone H2A-Bbd type 2/3 Antibodies

AND H2AB2 ELISA kits, Histone H2A-Bbd type 2/3 Proteins

Many biological assays use antibodies to detect Histone H2A-Bbd type 2/3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2A-Bbd type 2/3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2A-Bbd type 2/3 antibodies...

We validate the specificity of these antibodies to Histone H2A-Bbd type 2/3 by testing them on tissues known to express H2AB2 positively and negatively. Browse below to find the H2AB2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H2AB2 Infographic by Boster Bio

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Histone H2A Bbd (H2AFB2) (NM_001017991) Human Over-expression Lysate

Human

$628
Cat # LS474381
20 µg, 100 µg

H2AB2 Overview

Facts about Histone H2A-Bbd type 2/3.

H2AB2 3D structure. Source: alphafold

Histone H2A-Bbd type 2/3 (H2AB2)

Atypical histone H2A which may replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, restricting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo.

Gene Information

Human
Gene Name:	H2AB2
Uniprot:	P0C5Z0
Entrez:	474381

Family

Belongs to:

histone H2A family

Alternative Names

Histone H2A-Bbd type 2/3

Molecular Weight

Mass (kDA):
12.713 kDA

Genomic Context


Human

Location:	Xq28
Sequence:	X; NC_000023.11 (155380709..155381299)

Tissue Specificity

Present in mature sperm.

Subcellular Localizations

Nucleus. Chromosome. Associated with the active X chromosome and with autosomes, while it is absent from the inactive X chromosome and excluded from Barr bodies.

Interacting Proteins

HIST1H2BC

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H2AB2

References

PMID: 11266453 by Chadwick B.P., et al. A novel chromatin protein, distantly related to histone H2A, is largely excluded from the inactive X chromosome.

PMID: 15257289 by Bao Y., et al. Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA.