Helicase POLQ-like Antibodies

AND HELQ ELISA kits, Helicase POLQ-like Proteins

Many biological assays use antibodies to detect Helicase POLQ-like, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Helicase POLQ-like in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Helicase POLQ-like antibodies...

We validate the specificity of these antibodies to Helicase POLQ-like by testing them on tissues known to express HELQ positively and negatively. Browse below to find the HELQ antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: CMTM1

HELQ Infographic by Boster Bio

All HELQ Products

Product

Figures

Specificity

Applications

Price

Anti-Helicase POLQ-like HELQ Antibody

1 Q&As

Human, Mouse, Rat

IHC, WB

$405
Cat # A09185
100ul

HELQ Overview

Facts about Helicase POLQ-like.

HELQ 3D structure. Source: alphafold

Helicase POLQ-like (HELQ)

Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase (PubMed:11751861). Involved in the repair of DNA cross- links and double-strand break (DSB) resistance.

Participates in FANCD2-mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links (PubMed:19995904).

Gene Information

Human
Gene Name:	HELQ
Uniprot:	Q8TDG4
Entrez:	113510

Family

Belongs to:

helicase family

Alternative Names

EC 3.6.1; EC 3.6.4.12; Hel308; HEL308DNA helicase HEL308; helicase POLQ-like; helicase, POLQ-like; MGC20604; Mus308-like helicase; POLQ-like helicase

Molecular Weight

Mass (kDA):
124.131 kDA

Genomic Context


Human

Location:	4q21.23
Sequence:	4; NC_000004.12 (83407343..83455883, complement)

Diseases

Neoplasms
Nerve Degeneration
Genetic Diseases, Inborn
Genomic Instability
Premature Aging Syndrome
Aneuploidy

Interacting Proteins

RAD51C

Pathways

Dna Replication
Cell Death
Dna Repair
Menopause

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HELQ

References

PMID: 11751861 by Marini F., et al. A human DNA helicase homologous to the DNA cross-link sensitivity protein Mus308.

PMID: 19995904 by Moldovan G.L., et al. DNA polymerase POLN participates in cross-link repair and homologous recombination.