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- Table of Contents
Facts about Helicase POLQ-like.
Participates in FANCD2-mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links (PubMed:19995904).
Human | |
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Gene Name: | HELQ |
Uniprot: | Q8TDG4 |
Entrez: | 113510 |
Belongs to: |
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helicase family |
EC 3.6.1; EC 3.6.4.12; Hel308; HEL308DNA helicase HEL308; helicase POLQ-like; helicase, POLQ-like; MGC20604; Mus308-like helicase; POLQ-like helicase
Mass (kDA):
124.131 kDA
Human | |
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Location: | 4q21.23 |
Sequence: | 4; NC_000004.12 (83407343..83455883, complement) |
PMID: 11751861 by Marini F., et al. A human DNA helicase homologous to the DNA cross-link sensitivity protein Mus308.
PMID: 19995904 by Moldovan G.L., et al. DNA polymerase POLN participates in cross-link repair and homologous recombination.