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- Table of Contents
Hexokinase-2 Antibodies
AND HK2 ELISA kits, Hexokinase-2 Proteins
Many biological assays use antibodies to detect Hexokinase-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hexokinase-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hexokinase-2 antibodies...
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HK2 Infographic by Boster Bio
All HK2 Products
Product
Figures
Specificity
Applications
Price
Anti-Hexokinase II/HK2 Antibody Picoband®
8 Citations 1 Q&As
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A01389
100 μg/vial
Cat # A01389
100 μg/vial
Human, Rat
Flow Cytometry, WB
$482
Cat # M01389
100ul
Cat # M01389
100ul
Human
ELISA, Flow Cytometry, IF, IHC, WB
$380
Cat # M01389-1
100ul
Cat # M01389-1
100ul
Enzyme Activity, SDS-PAGE
$289
Cat # PROTP52789
Starting from 10ug
Cat # PROTP52789
Starting from 10ug
Dog, Human, Mouse, Rat
Flow Cytometry, IF, WB
$523
Cat # M01389-3
100 µl
Cat # M01389-3
100 µl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01389-4
20μL, 40μL, 100μL, 200μL
Cat # M01389-4
20μL, 40μL, 100μL, 200μL
HK2 Overview
Facts about Hexokinase-2.
Hexokinase-2 (HK2)
Gene Information
| Human | |
|---|---|
| Gene Name: | HK2 |
| Uniprot: | P52789 |
| Entrez: | 3099 |
Family
| Belongs to: |
|---|
| hexokinase family |
Alternative Names
DKFZp686M1669; EC 2.7.1; Hexokinase 2; Hexokinase type II; HK2; HKII; HXK2; Muscle form hexokinase; muscle
Molecular Weight
Mass (kDA):
102.38 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p12 |
| Sequence: | 2; NC_000002.12 (74834126..74893359) |
Tissue Specificity
Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
Subcellular Localizations
Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytosol. The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880). The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880). Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175).
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Neoplasms
- Prostatic Hyperplasia
- Hyperplasia
- Benign Prostatic Hypertrophy
- Carcinoma
- Neoplasm Metastasis
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Adenocarcinoma
Interacting Proteins
- MAGEA12
- Src
- TIGAR
- UBQLN1
Pathways
- Glycolysis
- Cell Proliferation
- Secretion
- Cell Death
- Pathogenesis
- Cell Cycle
- Localization
- Cell Growth
- Angiogenesis
- Transport
- Reverse Transcription
- Transdifferentiation
- Proteolysis
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Biotinylation
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HK2
bosterbio.com/bosterbio-gene-info-cards/HK2
References
PMID: 8250948 by Deeb S.S., et al. Human hexokinase II: sequence and homology to other hexokinases.
PMID: 8786021 by Lehto M., et al. Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity.
1 Publications of Boster Hexokinase-2 Antibodies & ELISA Kits
- PubMed ID: 32768579, Chen J,Wu D,Dong Z,Chen A,Liu S.The expression and role of glycolysis-associated...
*More publications can be found for each product on its corresponding product page