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- Table of Contents
Hexokinase-2 Antibodies
AND HK2 ELISA kits, Hexokinase-2 Proteins
Many biological assays use antibodies to detect Hexokinase-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hexokinase-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hexokinase-2 antibodies...
Designing a Western blot for Hexokinase-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HK2 Western Blot GuideHK2 Infographic by Boster Bio
All HK2 Products
Product
Figures
Specificity
Applications
Price
Anti-Hexokinase II/HK2 Antibody Picoband®
6 Citations
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A01389
100 μg/vial
Cat # A01389
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01389-4
20μL, 40μL, 100μL, 200μL
Cat # M01389-4
20μL, 40μL, 100μL, 200μL
Enzyme Activity, SDS-PAGE
$289
Cat # PROTP52789
Starting from 10ug
Cat # PROTP52789
Starting from 10ug
HK2 Overview
Facts about Hexokinase-2.
Hexokinase-2 (HK2)
Gene Information
| Human | |
|---|---|
| Gene Name: | HK2 |
| Uniprot: | P52789 |
| Entrez: | 3099 |
Family
| Belongs to: |
|---|
| hexokinase family |
Alternative Names
DKFZp686M1669; EC 2.7.1; Hexokinase 2; Hexokinase type II; HK2; HKII; HXK2; Muscle form hexokinase; muscle
Molecular Weight
Mass (kDA):
102.38 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p12 |
| Sequence: | 2; NC_000002.12 (74834126..74893359) |
Tissue Specificity
Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
Subcellular Localizations
Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytosol. The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880). The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880). Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175).
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Neoplasms
- Prostatic Hyperplasia
- Hyperplasia
- Benign Prostatic Hypertrophy
- Carcinoma
- Neoplasm Metastasis
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Adenocarcinoma
Interacting Proteins
- MAGEA12
- Src
- TIGAR
- UBQLN1
Pathways
- Glycolysis
- Cell Proliferation
- Secretion
- Cell Death
- Pathogenesis
- Cell Cycle
- Localization
- Cell Growth
- Angiogenesis
- Transport
- Reverse Transcription
- Transdifferentiation
- Proteolysis
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Biotinylation
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HK2
bosterbio.com/bosterbio-gene-info-cards/HK2
References
PMID: 8250948 by Deeb S.S., et al. Human hexokinase II: sequence and homology to other hexokinases.
PMID: 8786021 by Lehto M., et al. Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity.
1 Publications of Boster Hexokinase-2 Antibodies & ELISA Kits
- PubMed ID: 32768579, Chen J,Wu D,Dong Z,Chen A,Liu S.The expression and role of glycolysis-associated...
*More publications can be found for each product on its corresponding product page