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- Table of Contents
HNRNPL Antibodies
AND HNRNPL ELISA kits, HNRNPL Proteins
Many biological assays use antibodies to detect HNRNPL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HNRNPL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HNRNPL antibodies...
Designing a Western blot for HNRNPL? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HNRNPL Western Blot GuideHNRNPL Infographic by Boster Bio
All HNRNPL Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03769-4
100 μg/vial
Cat # A03769-4
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # A03769
100 μg/vial
Cat # A03769
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A09030-3
100 μg/vial
Cat # A09030-3
100 μg/vial
HNRNPL Overview
Facts about Heterogeneous nuclear ribonucleoprotein L.
Heterogeneous nuclear ribonucleoprotein L (HNRNPL)
Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements (PubMed:11809897, PubMed:22570490, PubMed:24164894, PubMed:25623890, PubMed:26051023).
Part of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and correlated with the majority of nascent transcripts (PubMed:2687284). Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter (PubMed:11809897).
Gene Information
| Human | |
|---|---|
| Gene Name: | HNRNPL |
| Uniprot: | P14866 |
| Entrez: | 3191 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FLJ35509; heterogeneous nuclear ribonucleoprotein L; hnRNP L; hnRNP-L; HNRPL
Molecular Weight
Mass (kDA):
64.133 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.2 |
| Sequence: | 19; NC_000019.10 (38836370..38852347, complement) |
Subcellular Localizations
Nucleus, nucleoplasm. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. These granules are not identical with P bodies or stress granules.
Diseases
- Glioblastoma Multiforme
- Ataxia
- Glioblastoma
- Hypoxia
- Tissue Adhesions
- Spermatogenesis Abnormal
- Physiological Stress
- Malignant Neoplasms
- Nervousness
- Azoospermia
Interacting Proteins
- HNRNPA2B1
- ILF3
- VHL
Pathways
- Translation
- Cell Adhesion
- Dna Repair
- Pathogenesis
- Spermatogenesis
PTMs
Research Areas
- Core ESC-Like Genes
- DNA Repair
- DNA replication, Transcription, Translation and Splicing
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNRNPL
bosterbio.com/bosterbio-gene-info-cards/HNRNPL
References
PMID: 11280764 by Ito M., et al. Molecular basis of T cell-mediated recognition of pancreatic cancer cells.
PMID: 2687284 by Pinol-Roma S., et al. A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts.