HS3ST3A1 Antibodies

AND HS3ST3A1 ELISA kits, HS3ST3A1 Proteins

Many biological assays use antibodies to detect HS3ST3A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HS3ST3A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HS3ST3A1 antibodies...

We validate the specificity of these antibodies to HS3ST3A1 by testing them on tissues known to express HS3ST3A1 positively and negatively. Browse below to find the HS3ST3A1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HS3ST3A1 Infographic by Boster Bio

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HS3ST3A1 Overview

Facts about Heparan sulfate glucosamine 3-O-sulfotransferase 3A1.

HS3ST3A1 3D structure. Source: alphafold

Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (HS3ST3A1)

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2.

The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate.

Gene Information

Human
Gene Name:	HS3ST3A1
Uniprot:	Q9Y663
Entrez:	9955

Family

Belongs to:

sulfotransferase 1 family

Alternative Names

3-OST-3A; 3OST3A1heparan sulfate glucosamine 3-O-sulfotransferase 3A1,30ST3A1heparin-glucosamine 3-O-sulfotransferase; EC 2.8.2; EC 2.8.2.30; h3-OST-3A; heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1; Heparan sulfate 3-O-sulfotransferase 3A1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; HS3ST3A

Molecular Weight

Mass (kDA):
44.9 kDA

Genomic Context


Human

Location:	17p12
Sequence:	17; NC_000017.11 (13494032..13601929, complement)

Tissue Specificity

Ubiquitous. Most abundant in heart and placenta, followed by liver and kidney.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Adenocarcinoma
Neoplasm Metastasis
Papilloma
Respiratory Papillomatosis
Polyps
Laryngeal Neoplasm
Malaria, Falciparum
Malignant Neoplasm Of Lung
Pregnancy Complications, Infectious
Exostoses
Virus Diseases
Papillomatosis
Malignant Neoplasms

Neoplasms
Hiv Infections
Vertical Disease Transmission
Malaria
Parasitemia
Respiratory Tract Neoplasms
Vocal Cord Polyp

Pathways

Reverse Transcription
Glycosylation
Cell Growth
Cell Communication

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HS3ST3A1

References

PMID: 9988767 by Shworak N.W., et al. Multiple isoforms of heparan sulfate D-glucosaminyl 3-O- sulfotransferase. Isolation, characterization, and expression of human cDNAs and identification of distinct genomic loci.

PMID: 10520990 by Shukla D., et al. A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry.